What is the Difference Between Zolpidem and Zolpidem Tartrate?

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Zolpidem and Zolpidem Tartrate are two versions of the same drug, which is mainly used for the short-term treatment of sleeping problems. The key difference between them is:

  • Zolpidem: This is the medication itself, belonging to a group of medicines called hypnotics. It acts on the brain to help with sleep and is used to treat various sleeping problems.
  • Zolpidem Tartrate: This is the active ingredient in Zolpidem tablets. It is slightly soluble in water and practically insoluble in dichloromethane. Its half-life is two to three times longer than that of Zolpidem, which allows it to promote longer periods of sleep.

In summary, Zolpidem is the medication used to treat sleeping problems, while Zolpidem Tartrate is the active ingredient in Zolpidem tablets. Both versions of the drug act on the brain to help with sleep, but the Tartrate version has a longer half-life, promoting continued sleep.

Comparative Table: Zolpidem vs Zolpidem Tartrate

Zolpidem and zolpidem tartrate are often used interchangeably, but they are not exactly the same. The key difference between them is that zolpidem is a medication primarily used for treating sleeping problems, while zolpidem tartrate is the active ingredient in zolpidem tablets. Here is a summary of the differences in tabular form:

Feature Zolpidem Zolpidem Tartrate
Category Medication Active Ingredient
Usage Treating sleeping problems Main ingredient in zolpidem tablets
Brand Name Ambien -
Extended-Release Form - Ambien CR
Borderline Used as a temporary medication -
Classification Schedule IV controlled substance -

Both zolpidem and zolpidem tartrate are used in the short-term treatment of insomnia and belong to a group of medications known as hypnotics. They work by acting on the brain to help with sleep. However, the medication contains additional inactive ingredients, including a treatment-emergent adverse event.