What is the Difference Between Zinc Picolinate and Zinc Gluconate?

🆚 Go to Comparative Table 🆚

Zinc picolinate and zinc gluconate are both inorganic salt compounds derived from organic acids, which serve as supplements to provide zinc, an essential mineral for various bodily functions. The main differences between zinc picolinate and zinc gluconate include their chemical composition, absorption, and taste.

  1. Chemical Composition: Zinc picolinate is derived from picolinic acid, while zinc gluconate is derived from gluconic acid. The chemical formula of zinc picolinate is C12H8N2O4Zn, and the chemical formula of zinc gluconate is C12H22O14Zn.
  2. Absorption: Research studies suggest that zinc picolinate is better absorbed by the human body compared to zinc gluconate. In one study, urine and erythrocyte zinc levels rose significantly during zinc picolinate administration, while there was no significant change in these parameters with zinc gluconate administration.
  3. Taste: Zinc gluconate is known for its mild taste and moderate bioavailability, making it a suitable option for those who are sensitive to the taste of zinc supplements.

In summary, zinc picolinate is considered to have better absorption compared to zinc gluconate, but zinc gluconate has a milder taste. Both forms can be used as supplements to provide zinc, which is essential for various bodily functions, such as supporting immune function, skin health, and hormonal balance.

Comparative Table: Zinc Picolinate vs Zinc Gluconate

Zinc picolinate and zinc gluconate are inorganic salt compounds derived from organic acids, which serve as zinc supplements. Here is a comparison between the two:

Property Zinc Picolinate Zinc Gluconate
Derived from Picolinic acid Gluconic acid
Absorption Better absorbed than some other forms of zinc, including zinc gluconate and zinc citrate Well absorbed, but may not be as well absorbed as zinc picolinate
Cadmium content Contains nitrogen atoms Does not contain nitrogen atoms
Melting point Ranges from 172 to 175 °C Not specified
Chemical formula C12H22O14Zn C6H12O7Zn
Molar mass 455.68 g/mol Not specified
Common forms Capsules, tablets, and lozenges Throat lozenges

Both zinc picolinate and zinc gluconate are taken orally as supplements and have organic acids as their parent compounds. While zinc picolinate is derived from picolinic acid and may be better absorbed by the human body, zinc gluconate is derived from gluconic acid and is often found in throat lozenges.