What is the Difference Between Zantac and Prilosec?

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Zantac and Prilosec are both medications used to treat stomach problems such as heartburn and sour stomach, but they work differently. Here are the main differences between the two:

  1. Mechanism of action: Zantac is an H2 (histamine-2) blocker that inhibits the action of histamine on the cells, reducing the production of acid by the stomach. Prilosec, on the other hand, is a proton pump inhibitor (PPI) that blocks the production of acid by the stomach directly.
  2. Potency and duration: Prilosec builds up in your system, making it more potent and longer-lasting than Zantac. However, Zantac works more quickly than Prilosec because it does not have to build up in your system to work.
  3. Side effects: Both drugs have similar side effects, such as abdominal discomfort or diarrhea. However, these side effects are usually minimal and decrease over time.
  4. Availability: Both Zantac and Prilosec can be purchased over the counter.

Both drugs treat similar conditions, including heartburn, stomach upset, and other acid reflux-related issues. It is essential to consult your doctor or pharmacist to decide which medication is suitable for your specific needs.

Comparative Table: Zantac vs Prilosec

Zantac and Prilosec are both medications used to treat stomach problems such as heartburn and sour stomach, but they work differently and belong to different drug classes. Here is a comparison table of the differences between Zantac and Prilosec:

Feature Zantac Prilosec
Drug Class H2 (histamine-2) blocker Proton Pump Inhibitor (PPI)
Mechanism of Action Blocks a chemical called histamine that activates stomach acid pumps Works directly on acid pumps in the stomach to reduce acid production
Brand Name Famotidine (Zantac 360) Omeprazole
Side Effects Constipation, diarrhea, fatigue, headache, drowsiness, dizziness, sleep problems, decreased sex drive Headache, nausea, vomiting, diarrhea, stomach pain, gas, constipation, fever, or cold symptoms
Availability Prescription and Over-the-Counter (OTC) Prescription and Over-the-Counter (OTC)

Both Zantac and Prilosec are available in prescription and OTC forms and can treat conditions caused by stomach acid, such as gastroesophageal reflux disease (GERD), erosive esophagitis, and Zollinger-Ellison syndrome. It is essential to consult your doctor or pharmacist to determine which medication is suitable for your specific needs.