What is the Difference Between X-ray Crystallography and X-ray Diffraction?

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X-ray crystallography and X-ray diffraction are related but distinct techniques used to study the structure of materials. The main differences between them are:

  • Purpose: X-ray crystallography is an experimental science that determines the atomic and molecular structure of crystalline materials. X-ray diffraction, on the other hand, is a phenomenon in which the atoms of a crystal cause an interference pattern, and it is a more general technique used to study the structure of a wide range of materials.
  • Applications: X-ray crystallography is a specialized application of X-ray diffraction specifically used for determining the atomic arrangement within crystalline materials. X-ray diffraction can be applied to various forms of materials, not just crystalline ones.
  • Measurements: In X-ray crystallography, a crystallographer can measure the angles and intensities of the diffracted beams to produce a 3D image of the electron density of the crystal. This allows for the determination of the mean positions of the atoms in the crystal. In X-ray diffraction, the focus is on the interference pattern caused by the atoms, rather than the specific atomic arrangement.

In summary, X-ray crystallography is a technique used to determine the atomic and molecular structure of crystalline materials, while X-ray diffraction is a more general technique used to study the structure of a wide range of materials.

Comparative Table: X-ray Crystallography vs X-ray Diffraction

X-ray crystallography and X-ray diffraction are important analytical techniques used to study the atomic and molecular structure of crystals. Here is a table summarizing the differences between the two:

X-ray Crystallography X-ray Diffraction
Determines the atomic and molecular structure of a crystal Encompasses the scattering of X-rays by any kind of material, not just crystals
Experimental science Chemical technique
Requires a ordered, periodic structure of atoms Can analyze a wide range of forms of the material
Crystallographer measures angles and intensities of diffracted beams to produce a 3D picture of electron density Measures the angles and intensities of scattered X-rays, which are recorded as the crystal is gradually rotated

In summary, X-ray crystallography focuses on determining the atomic and molecular structure of crystals, while X-ray diffraction is a broader technique that studies the scattering of X-rays by any material. X-ray crystallography is an experimental science, whereas X-ray diffraction is a chemical technique.