What is the Difference Between X Linked Dominant and X Linked Recessive?
🆚 Go to Comparative Table 🆚The difference between X-linked dominant and X-linked recessive inheritance lies in the way the genetic disorders are passed down through generations and the affected individuals. Here are the key differences:
X-linked Dominant:
- A single mutated gene on the X chromosome is sufficient to cause the disorder in both males and females.
- Males and females are equally affected by the disorder.
- Fathers cannot pass X-linked traits to their sons, but mothers can pass X-linked genes to both sons and daughters.
X-linked Recessive:
- Affected males have a single altered copy of the gene on their X chromosome, while unaffected females have a second, normal copy of the gene.
- Males are affected almost exclusively, while females are generally unaffected carriers of the X-linked trait.
- Affected males cannot pass the condition to their sons, but all daughters will inherit the X chromosome and become carriers of the X-linked trait.
In summary, X-linked dominant disorders are caused by mutations in genes on the X chromosome and affect both males and females, while X-linked recessive disorders are caused by mutations in genes on the X chromosome and predominantly affect males.
Comparative Table: X Linked Dominant vs X Linked Recessive
X-linked dominant and X-linked recessive are two types of genetic inheritance patterns involving genes located on the X chromosome. Here are the key differences between them:
Mode of Inheritance: In X-linked dominant inheritance, a dominant gene on the X chromosome causes the disorder. In X-linked recessive inheritance, one or two copies of recessive genes on the X chromosomes cause the disorder.
Gender-specific affect: In X-linked dominant inheritance, only one copy of the mutant gene is sufficient to cause the disease in both males and females. In X-linked recessive inheritance, one copy of the mutant gene is sufficient to cause the disease in males, but both copies are needed to cause the disease in females.
Inheritance: X-linked dominant inheritance tends to occur in every generation of a family, with each affected person usually having one affected parent. Dominant mutations can also occur in an individual for the first time, with no family history of the condition. X-linked recessive inheritance often has a father who carries the mutated gene, passing it on to unaffected female carriers and affected males.
| Feature | X-linked Dominant | X-linked Recessive |
|---|---|---|
| Mode of Inheritance | Dominant gene on the X chromosome | Recessive gene(s) on the X chromosome |
| Gender-specific affect | One copy of the mutant gene sufficient for disease in both males and females | One copy of the mutant gene sufficient for disease in males, two copies needed for disease in females |
| Inheritance Pattern | Found in every generation of a family | Father carries the mutated gene, passes it to unaffected female carriers and affected males |
- Dominant vs Recessive
- Dominant vs Recessive Alleles
- Autosomal Dominant vs Autosomal Recessive Disorders
- X linked vs Y linked Inheritance
- Dominant vs Recessive Epistasis
- Dominance vs Codominance
- Autosomal vs X-Linked Pedigree
- Haploinsufficiency vs Dominant Negative
- Codominance vs Incomplete Dominance
- Autosomal Dominant vs Recessive Polycystic Kidney Disease
- Codominance vs Multiple Alleles
- Dominance vs Epistasis
- Homozygous vs Heterozygous
- Mendelian vs Chromosomal Disorders
- Sex-linked vs Autosomal
- Homozygous vs Hemizygous
- X Inactivation vs Genomic Imprinting
- Mendelian vs Non Mendelian Inheritance
- Punnett Square vs Pedigree