What is the Difference Between Synapse and Synaptic Cleft?

The difference between a synapse and a synaptic cleft lies in their definition and function. Here are the key distinctions:

• Synapse: A synapse is a junction between two neurons, where nerve impulses are transferred from the axon of a presynaptic (sending) neuron to the dendrite of a postsynaptic (receiving) neuron through a neurotransmitter. Synapses are part of the network that connects sensory organs in the peripheral nerves to the brain and between nerves in the brain and neurons throughout the body.
• Synaptic Cleft: The synaptic cleft, also known as the synaptic gap, is the small space between the axon terminal of the presynaptic neuron and the membrane of the postsynaptic cell. This gap is typically 0.02 microns wide. The synaptic cleft is where the neurotransmitters are released from the presynaptic neuron and bind to specific receptors on the postsynaptic neuron.

In summary, a synapse is the point of contact between two neurons where nerve impulses are transferred, while the synaptic cleft is the gap between the presynaptic and postsynaptic neurons where neurotransmitters are released and bind to their receptors.

Comparative Table: Synapse vs Synaptic Cleft

Here is a table comparing the differences between a synapse and a synaptic cleft:

In summary, a synapse is the junction between two neurons, responsible for transmitting nerve impulses, while the synaptic cleft is the specific gap between pre- and post-synaptic membranes that plays a crucial role in the transfer of neurotransmitters between neurons.