What is the Difference Between Symmetric and Asymmetric Karyotype?

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The main difference between symmetric and asymmetric karyotypes lies in the size, shape, and distribution of chromosomes within the nucleus of a cell.

Symmetric Karyotype:

  • Shows little differences in the size of chromosomes of the set.
  • Consists of more metacentric chromosomes.
  • Represents a primitive state.

Asymmetric Karyotype:

  • Has large differences between the sizes of chromosomes.
  • Contains fewer metacentric chromosomes and more acrocentric or telocentric chromosomes.
  • Represents a more advanced feature compared to symmetric karyotype.
  • Examples of organisms with asymmetric karyotypes include Ginkgo biloba.

Both symmetric and asymmetric karyotypes can be useful in chromosome banding, chromosome aberrations, and diagnosis of parental genetic effects.

Comparative Table: Symmetric vs Asymmetric Karyotype

Here is a table comparing the differences between symmetric and asymmetric karyotypes:

Feature Symmetric Karyotype Asymmetric Karyotype
Chromosome Size Differences Shows little differences in the size of chromosomes Has major differences between the large and small size of chromosomes
Metacentric Chromosomes Consists of more metacentric chromosomes Has fewer metacentric chromosomes
Centromere Position Chromosomes have medium or sub-median centromeres Chromosomes may have different centromere positions
Evolutionary Significance Asymmetric karyotypes are considered more advanced than symmetric karyotypes Asymmetric karyotypes are considered less advanced than symmetric karyotypes
Chromosome Aberrations Karyotypes help in the identification of chromosomal aberrations Karyotypes help in the identification of chromosomal aberrations
Prenatal Genetic Defects Karyotypes are helpful in diagnosing prenatal genetic defects Karyotypes are helpful in diagnosing prenatal genetic defects

Karyotypes are diagrams that show the correct number and structure of the complete set of chromosomes in the nucleus of the cell, which are visible mostly during the metaphase of cell division. They are useful in chromosome banding and help in studying structural features of each chromosome.