What is the Difference Between Squamous Cell Carcinoma and Adenocarcinoma Cervix?

The main differences between squamous cell carcinoma and adenocarcinoma of the cervix are the types of cells they originate from and their prevalence. Here are the key differences:

Origin: Squamous cell carcinoma develops from cells in the ectocervix (outer part of the cervix), while adenocarcinoma develops in the glandular cells of the endocervix (inner part of the cervix).
Prevalence: Squamous cell carcinoma accounts for up to 90% of cervical cancers, making it the most common type. Adenocarcinoma, on the other hand, accounts for between 10% and 20% of cervical cancers.
Mixed Carcinoma: In some cases, cervical cancer may have features of both squamous cell carcinoma and adenocarcinoma, which is called mixed carcinoma or adenosquamous carcinoma.

Both squamous cell carcinoma and adenocarcinoma are typically treated in the same way, as cervical cancers.

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What is the Difference Between Squamous Cell Carcinoma and Adenocarcinoma Cervix?

Comparative Table: Squamous Cell Carcinoma vs Adenocarcinoma Cervix

Here is a table comparing the differences between squamous cell carcinoma (SCC) and adenocarcinoma (ADC) of the cervix:

Feature	Squamous Cell Carcinoma (SCC)	Adenocarcinoma (ADC)
Histological Type	Most frequently diagnosed type of cervical cancer	Less common than SCC, but incidence has increased in recent decades
Risk Factors	Shares many risk factors with adenocarcinoma, but may have some unique risk factors	Shares many risk factors with squamous cell carcinoma, but may have some unique risk factors
MolecularDifferences	Over-expressed and under-expressed genes differ between the two histological types	Over-expressed and under-expressed genes differ between the two histological types
Treatment Outcomes	Treatment outcomes may vary depending on the type of radiotherapy or concurrent chemoradiotherapy used	Patients with adenocarcinoma have poorer overall survival (OS) and disease-free survival (DFS) regardless of treatment with radiotherapy alone or chemoradiotherapy

Please note that this table is based on the available search results and may not provide a complete comparison of all differences between squamous cell carcinoma and adenocarcinoma of the cervix.

Guilherme Mazui is graduated in journalism from the Federal University of Minas Gerais (UFMG) and a master's degree in Communication from the University of São Paulo (USP). In addition, he has experience in advertising writing and has worked as a content editor in several companies.