What is the Difference Between SGOT and SGPT?
🆚 Go to Comparative Table 🆚SGOT (Serum Glutamic Oxaloacetic Transaminase) and SGPT (Serum Glutamic Pyruvic Transaminase) are enzymes that serve as indicators of liver health. The main differences between SGOT and SGPT are their specificity to the liver and the conditions that can cause elevated levels.
- SGOT: This enzyme is found in various tissues, including the liver, kidney, muscles, heart, and brain. Elevated SGOT levels can occur during liver complications, heart attacks, or muscle injuries. It measures the levels of the enzyme in the blood, which is normally found in the liver, heart, muscle, and other tissues.
- SGPT: This enzyme is predominantly found in the liver. Elevated SGPT levels can arise during liver diseases or damage to any tissues in the liver. It measures the levels of the enzyme in the blood, which is primarily found in the liver.
Both SGPT and SGOT tests are performed using a blood sample and are part of a liver function test panel. The normal ranges for SGOT and SGPT can vary depending on the laboratory, but typically, the normal range for SGOT is 5 to 40 units per liter of serum, while the normal range for SGPT is 7 to 56 units per liter of serum. High levels of these enzymes can indicate various complications, especially with liver diseases or damage.
Comparative Table: SGOT vs SGPT
SGOT (Serum Glutamic Oxaloacetic Transaminase) and SGPT (Serum Glutamic Pyruvic Transaminase) are two enzymes produced by the liver that are used to assess liver function and health. Here is a table highlighting the differences between SGOT and SGPT:
| Feature | SGOT (AST) | SGPT (ALT) |
|---|---|---|
| Enzyme | Serum Glutamic Oxaloacetic Transaminase | Serum Glutamic Pyruvic Transaminase |
| Synonym | Aspartate Aminotransferase (AST) | Alanine Aminotransferase (ALT) |
| Specificity | Less liver-specific, found in various tissues such as liver, heart, muscle, and kidney | More liver-specific, primarily found in the liver |
| Normal Range | 5 to 40 units per liter of serum | 7 to 56 units per liter of serum |
| Conditions | Elevated in heart attacks or muscle injuries | Elevated in liver injury, such as acute viral hepatitis A |
Both SGOT and SGPT tests are performed using a blood sample and are part of a liver function test panel. The difference between the two tests is the enzyme they measure, and they are used to assess liver health and diagnose liver diseases.