What is the Difference Between SDP and RDP?
🆚 Go to Comparative Table 🆚The main difference between Single Donor Platelets (SDP) and Random Donor Platelets (RDP) lies in their preparation methods, volume, and cost. Here are the key differences:
- Preparation Method: SDP is prepared using an apheresis technique, while RDP is prepared by centrifugation.
- Volume: One RDP unit contains platelets concentrated in 40-70 ml of plasma, while one SDP unit contains platelets concentrated in 200-300 ml of plasma. Between 5 and 6 units of RDP are equivalent to 1 unit of SDP.
- Cost: SDP is more costly than RDP.
Both SDP and RDP are used to treat patients with thrombocytopenia or platelet dysfunction, but SDP is considered a newer, more advanced, and effective technique compared to RDP. The choice between the two methods depends on factors such as patient need, availability, and cost.
Comparative Table: SDP vs RDP
Here is a table comparing the differences between Single Donor Platelets (SDP) and Random Donor Platelets (RDP):
| Feature | SDP | RDP |
|---|---|---|
| Source | Single donor | Multiple donors (4-5) |
| Process | Platelet apheresis machine | Centrifuging whole blood |
| Platelet Count | Contains a higher number of platelets | Contains a lower number of platelets |
| Plasma Volume | 200-300 ml of plasma | 40-70 ml of plasma |
| Cost | More expensive | Less expensive |
| Leucoreduction | Easier to perform | Difficult to perform |
Both SDP and RDP are types of platelet transfusion methods used to prevent bleeding. They have similar effectiveness, post-transfusion increment, platelet survival, and hemostatic effect. However, the key difference between the two methods is the source of platelets: SDP uses a single donor, while RDP requires whole blood from multiple donors. Additionally, SDP is more expensive and more difficult to perform leucoreduction compared to RDP.