What is the Difference Between Sarcolemma and Sarcoplasmic Reticulum?

🆚 Go to Comparative Table 🆚

The sarcolemma and sarcoplasmic reticulum are two distinct components of muscle cells. The main differences between them are:

  1. Function: The sarcolemma is the plasma membrane that lines the muscle fiber, while the sarcoplasmic reticulum is the smooth endoplasmic reticulum of the muscle cell.
  2. Structure: The sarcolemma is composed of a phospholipid bilayer with hydrophilic heads and hydrophobic tails, and also contains an outer polysaccharide layer known as the glycocalyx. The sarcoplasmic reticulum, on the other hand, is a network of tubes and sacs that play a crucial role in the synthesis, modification, and transport of cellular products.
  3. Location: The sarcolemma forms the dynamic outer membrane of the muscle cell and separates the muscle cell contents from the surrounding environment. The sarcoplasmic reticulum is located within the myocyte, surrounding each myofibril.

Both the sarcolemma and sarcoplasmic reticulum are involved in the calcium physiology of the muscle cell. The sarcolemma and sarcoplasmic reticulum work together to facilitate the function of myocytes, which are the muscle fibers that form the bulk of muscle tissue.

Comparative Table: Sarcolemma vs Sarcoplasmic Reticulum

Here is a table comparing the differences between the sarcolemma and the sarcoplasmic reticulum:

Feature Sarcolemma Sarcoplasmic Reticulum
Definition The plasma membrane that surrounds the muscle cell. The smooth endoplasmic reticulum of the muscle cell, responsible for storing, releasing, and retrieving calcium ions.
Function Forms the dynamic outer membrane and acts as a boundary to the muscle cell contents. Stores calcium ions and plays a role in muscle contraction.
Composition Composed of a phospholipid bilayer with hydrophilic heads and hydrophobic tails, and an outer polysaccharide layer known as the glycocalyx. Composed of a protein called Calsequestrin, which acts as a calcium-binding protein.
Location Surrounds the muscle cell. Found within the muscle cell, wrapping around myofibrils.
Role in Muscle Contraction Action potential conduction triggers muscle contraction. Releases calcium ions to be used for muscle contraction.

The sarcolemma is the plasma membrane that surrounds the muscle cell, while the sarcoplasmic reticulum is the smooth endoplasmic reticulum of the muscle cell that plays a crucial role in muscle contraction by storing and releasing calcium ions.