What is the Difference Between Salicylic Acid and Acetylsalicylic Acid?

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Salicylic acid and acetylsalicylic acid are both derivatives of salicylic acid, but they have different chemical structures and applications. The main differences between the two are:

  1. Chemical Structure: Salicylic acid has a carboxyl group and a hydroxyl group in its molecular structure, while acetylsalicylic acid is an ester of salicylic acid, forming from the esterification of salicylic acid.
  2. Taste: Salicylic acid has a bitter taste, whereas acetylsalicylic acid, also known as aspirin, does not have the bitter taste that most derivatives of salicylic acid contain.
  3. Applications: Salicylic acid is primarily used to treat warts, dandruff, acne, and other skin disorders due to its ability to remove the outer layer of the skin. Acetylsalicylic acid, on the other hand, is used to reduce pain, fever, or inflammation.

In summary, the key differences between salicylic acid and acetylsalicylic acid are their chemical structures, tastes, and applications. Salicylic acid is used for various skin disorders, while acetylsalicylic acid is commonly used as a pain reliever and anti-inflammatory medication.

Comparative Table: Salicylic Acid vs Acetylsalicylic Acid

Salicylic acid and acetylsalicylic acid are two compounds with similar molecular structures but different properties and applications. Here is a table highlighting the differences between them:

Property Salicylic Acid Acetylsalicylic Acid
Chemical Formula C7H6O3 C9H8O4
IUPAC Name 2-hydroxybenzoic acid 2-acetoxybenzoic acid
Molar Mass 138.12 g/mol 180.16 g/mol
Appearance White crystalline solid, odorless White crystalline solid, odorless
Functional Group Alcohol group on the benzene ring Acetoxy group on the benzene ring
Medical Applications Removal of the outer layer of the skin, topical use in acne treatment Pain relief, fever reduction, and anti-inflammatory properties (Aspirin)
Side Effects Upset stomach, stomach ulcers, stomach bleeding (in some cases) Upset stomach, stomach ulcers, stomach bleeding (in some cases)

Salicylic acid is used for the removal of the outer layer of the skin and is commonly found in acne treatments. Acetylsalicylic acid, on the other hand, is a derivative of salicylic acid formed from the esterification of salicylic acid. It is commonly known as Aspirin and is widely used for pain relief, fever reduction, and anti-inflammatory properties.