What is the Difference Between Restrictive and Obstructive Pulmonary Disease?

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The main difference between restrictive and obstructive pulmonary diseases lies in the way they affect the lungs and their symptoms. Both types of lung diseases share the main symptom of shortness of breath with exertion.

Obstructive Lung Diseases:

  • Include conditions that make it difficult to exhale all the air in the lungs.
  • Caused by obstruction in the air passages, resulting in slow and shallow exhalation.
  • Examples of obstructive lung diseases include bronchiectasis, asthma, emphysema, and bronchiolitis.

Restrictive Lung Diseases:

  • Include conditions where it is difficult to fully expand the lungs with air.
  • Result from a reduction in the total volume of air that the lungs can hold, often due to a decrease in lung elasticity or a problem related to the chest wall.
  • Caused by the destruction of distal lung parenchyma due to toxins, inflammatory changes involving the alveolar interstitium, or extra parenchymal conditions.
  • Examples of restrictive lung diseases include interstitial lung disease, such as idiopathic pulmonary fibrosis, sarcoidosis, obesity hypoventilation syndrome, scoliosis, and neuromuscular diseases like muscular dystrophy or amyotrophic lateral sclerosis (ALS).

Diagnosis of both obstructive and restrictive lung diseases is typically done using pulmonary function tests, which measure the volume and flow of air through the lungs. Treatment for these lung diseases depends on the type and stage of the disease, family history, patient's medical history, and the health and age of the patient.

Comparative Table: Restrictive vs Obstructive Pulmonary Disease

Here is a table comparing the differences between restrictive and obstructive pulmonary diseases:

Measurement Obstructive Pattern Restrictive Pattern
Forced vital capacity (FVC) Decreased or normal Decreased
Forced expiratory volume in one second (FEV1) Decreased Decreased or normal
FEV1/FVC ratio Decreased Normal or increased
Total lung capacity (TLC) Normal or increased Decreased

Obstructive lung diseases make it difficult to exhale all the air in the lungs, while restrictive lung diseases make it difficult to fully expand the lungs with air. Some common obstructive lung diseases include chronic obstructive pulmonary disease (COPD), asthma, bronchiectasis, and cystic fibrosis. Restrictive lung diseases can be further classified into intrinsic (pulmonary fibrosis, conditions caused by inhaling dangerous pollutants) and extrinsic (obesity, scoliosis, pleural effusion) conditions. Symptoms of both types of lung diseases may include shortness of breath, wheezing, and a persistent cough.