What is the Difference Between Renin and Rennin?

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The main difference between renin and rennin lies in their function and origin. Renin is a hormone involved in the regulation of arterial blood pressure, while rennin is an enzyme that plays a role in milk coagulation. Here are the key differences between the two:

  • Renin:
  • Hormone produced by the kidneys.
  • Also known as angiotensinogen.
  • Involved in the renin-angiotensin-aldosterone system (RAAS), which regulates the body's water balance and blood pressure level.
  • Secreted by peptic (zymogen) cells of gastric glands into the stomach.
  • Main function is to hydrolyze angiotensinogen secreted from the liver into the peptide angiotensin I.
  • Rennin:
  • Enzyme found in the gastric juice of infants and ruminant animals.
  • Also known as chymosin.
  • Protein-digesting enzyme that curdles milk by converting caseinogen into insoluble casein.
  • Produced by the peptic cells of gastric glands present in the stomach.
  • Used in the commercial form of rennet, which is used in manufacturing cheese.

In summary, renin is a hormone that regulates blood pressure, while rennin is an enzyme that helps in the digestion of milk protein and is used in cheese production.

Comparative Table: Renin vs Rennin

Here is a table comparing the differences between renin and rennin:

Feature Renin Rennin
Function Regulates arterial blood pressure and electrolyte balance Involved in the digestion of milk
Type Hormone Enzyme
Molecular Weight Approximately 37 kDa Approximately 40 kDa
Source Produced in the kidneys Produced by the peptic cells of gastric glands in the stomach
Presence Found in mammals, including humans Found in the gastric juice of infants and calves' stomachs

In summary, renin is a hormone involved in regulating blood pressure and electrolyte balance, while rennin is an enzyme involved in the digestion of milk.