What is the Difference Between Pyruvate and Pyruvic Acid?

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The terms "pyruvate" and "pyruvic acid" are often used interchangeably, but there is a subtle difference between the two. Here are the key points:

  • Pyruvate: Pyruvate is a 2-oxo monocarboxylic acid anion, which means it is an ion with a negative charge on it. It is a conjugated base of pyruvic acid and is more stable at the pH found in the human body. Pyruvate plays a crucial role in human metabolic processes and is involved in the glycolysis process, where one molecule of glucose is broken down into two molecules of pyruvate.
  • Pyruvic Acid: Pyruvic acid is an organic acid that plays a vital role in human metabolic processes and occurs in all living cells. It is a colorless liquid with a smell similar to that of acetic acid and is miscible with water. Pyruvic acid is the end product of glycolysis and can release protons, making it capable of binding with a positively charged sodium.

In summary, the main difference between pyruvate and pyruvic acid is that pyruvate is the anion produced from pyruvic acid, with a negative charge on it, while pyruvic acid is the acid itself, capable of releasing protons. Both substances are involved in cellular respiration and energy production in living organisms.

Comparative Table: Pyruvate vs Pyruvic Acid

Pyruvate and pyruvic acid are related compounds involved in cellular metabolism. Here is a table highlighting the differences between them:

Feature Pyruvate Pyruvic Acid
Definition Pyruvate is the conjugate base of pyruvic acid and an anion. Pyruvic acid is an organic acid that plays a vital role in human metabolic processes.
Chemical Formula CH3COCOO− CH3COCOOH
Hydrogen Atoms Consists of 3 hydrogen atoms Consists of 4 hydrogen atoms
Charge Has an overall negative charge (anion). Neutral in nature, does not have any charge.
Proton and Electron Balance Pyruvic acid has the same number of electrons as protons. Pyruvate is the anion produced from pyruvic acid.
Stability Pyruvate is usually more stable at human body pH. Pyruvic acid is less stable at the pH value of the human body and tends to convert to pyruvate.

Pyruvate is formed during glycolysis, when one molecule of glucose is broken down into two molecules of pyruvate. Pyruvate can then be utilized in further reactions to produce energy. Pyruvic acid, on the other hand, is an organic liquid produced by the breakdown of carbohydrates and sugars through the glycolytic process.