What is the Difference Between Prilosec and Prilosec OTC?

The main difference between Prilosec and Prilosec OTC lies in their availability and the conditions they are used to treat. Both Prilosec and Prilosec OTC contain the same active ingredient, omeprazole, which effectively stops acid production. However, there are some key differences:

• Availability: Prilosec is a prescription medication, meaning it can only be obtained with a prescription from a certified doctor. On the other hand, Prilosec OTC can be purchased without a prescription, as the name "OTC" (over-the-counter) suggests.
• Dosage: Prescription Prilosec has a higher dosage compared to Prilosec OTC, which has a lower dosage. The prescription dosage may also be used for a longer period of time than when taken as an OTC.
• Conditions Treated: Prescription Prilosec is used to treat diseases and conditions that require diagnosis and supervision by a doctor, such as gastric and duodenal ulcers, and other inflamed gastrointestinal conditions. Prilosec OTC, on the other hand, is used to treat only the symptoms of frequent heartburn, which is defined as heartburn occurring 2 or more days a week. It is not intended for occasional heartburn or immediate relief of heartburn.

Despite these differences, both prescription Prilosec and Prilosec OTC contain the same active ingredient, omeprazole, which effectively stops acid production. While they have some differences in dosage and availability, both versions of the drug work in the same way to decrease stomach acid production.

Comparative Table: Prilosec vs Prilosec OTC

Here is a table comparing the differences between Prilosec and Prilosec OTC:

Both Prilosec and Prilosec OTC are proton pump inhibitors (PPIs) that effectively stop acid production. However, Prilosec (prescription) is typically used to treat more serious conditions such as ulcers and esophagitis, while Prilosec OTC is available over-the-counter for treating occasional heartburn, GERD, and indigestion. The dosage of prescription Prilosec is generally higher than that of Prilosec OTC, which has a lower dosage.