What is the Difference Between Polymyalgia Rheumatica and Rheumatoid Arthritis?

Polymyalgia rheumatica (PMR) and rheumatoid arthritis (RA) are both autoimmune conditions that cause joint pain and inflammation. However, they have distinct differences in terms of symptoms, affected areas, and severity. Here are the key differences between the two:

1. Affected areas: PMR typically causes pain and stiffness in the shoulders, neck, arms, and hips, while RA usually affects the hands, wrists, knees, shoulders, elbows, and ankles.
2. Swelling: RA causes joint swelling, while PMR does not.
3. Systemic effects: RA is a systemic disease that can affect the entire body, including the skin, eyes, mouth, blood vessels, and heart. PMR, on the other hand, does not have such wide-ranging effects.
4. Disease duration: PMR is a temporary condition that often lasts 1–5 years, while RA is a progressive, lifelong condition.
5. Severity: RA is generally considered more severe than PMR, as it can cause significant joint damage and affect other parts of the body.

Diagnosis and treatment for these conditions can be challenging due to their similarities. However, a trained rheumatologist can identify the unique features of each condition. Treatment for PMR usually involves oral prednisolone, while RA requires different medications, such as disease-modifying antirheumatic drugs (DMARDs) and biologic response modifiers.

Comparative Table: Polymyalgia Rheumatica vs Rheumatoid Arthritis

Polymyalgia rheumatica (PMR) and rheumatoid arthritis (RA) are both autoimmune conditions that affect the joints, causing pain and stiffness. However, there are differences between the two in terms of symptoms, affected joints, and treatment. Here is a table comparing the two conditions:

While PMR and RA share similarities, they have different causes and treatment methods. A proper diagnosis by a rheumatologist is crucial for determining the appropriate treatment plan.