What is the Difference Between Point Mutations and Indels?
🆚 Go to Comparative Table 🆚The main difference between point mutations and indels lies in the nature of the changes they cause in the DNA sequence. Here are the key differences:
- Point mutations are a type of substitution where one of the nucleotides in the DNA sequence is replaced without changing the overall number of nucleotides in the DNA. Point mutations can be classified into three main types: silent, missense, and nonsense mutations.
- Indels (insertion-deletion mutations) involve the insertion or deletion of one or more nucleotides in the DNA sequence. Indels can lead to frameshift mutations in coding regions of the genome if the length of the indel is not a multiple of three.
In summary, point mutations alter only one nucleotide without changing the overall number of nucleotides in the DNA, while indels change one or more nucleotides in the DNA sequence.
On this pageWhat is the Difference Between Point Mutations and Indels? Comparative Table: Point Mutations vs Indels
Comparative Table: Point Mutations vs Indels
Here is a table summarizing the differences between point mutations and indels:
| Feature | Point Mutations | Indels |
|---|---|---|
| Definition | Changes in one nucleotide in the DNA sequence | Insertion or deletion of one or more nucleotides in the DNA sequence |
| Types | Silent, missense, nonsense mutations | Insertions and deletions |
| Effects | Substitution, insertion, or deletion of a single nucleotide | Change in the number of nucleotides in the DNA sequence |
Point mutations involve the alteration of a single nucleotide, whereas indels involve the insertion or deletion of one or more nucleotides in the DNA sequence.
Read more:
- Frameshift Mutation vs Point Mutation
- Point Mutation vs Chromosomal Mutation
- Substitution Insertion vs Deletion Mutations
- SNP vs Mutation
- Mutation vs Mutagen
- DNA Damage vs Mutation
- Original vs Mutated Sequences
- Frameshift Mutation vs Base Substitution Mutation
- Mutation vs Recombination
- Mutation vs Polymorphism
- Forward vs Reverse Mutation
- Missense vs Nonsense Mutation
- DNA Sequence Mutations vs Epigenetic Modifications
- Spontaneous vs Induced Mutation
- Silent vs Neutral Mutation
- Mutation Rate vs Substitution Rate
- Gene Mutation vs Chromosome Mutation
- Synonymous vs Nonsynonymous Mutation
- Nondisjunction vs Translocation Mutations