What is the Difference Between Phentermine and Phendimetrazine Tartrate?

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Phentermine and phendimetrazine tartrate are both prescription medications that belong to the same drug class called anorectics, which are used to manage weight in people who are obese or overweight. However, they have some differences in terms of available forms, dosages, and restrictions:

  • Dosages: Phendimetrazine tartrate is available as a 35 mg tablet and 105 mg extended-release capsule, with the usual dosage being a 35 mg tablet two to three times daily one hour before meals. Phentermine is available in various forms, such as regular oral tablet, capsule, extended-release capsule, and orally disintegrating tablet, with strengths ranging from 15 to 37.5 mg.
  • Effectiveness: Phendimetrazine is considered more effective for weight loss than phentermine due to its stronger stimulant properties, which are more similar to amphetamines.
  • Side Effects: Both medications can cause side effects, but phendimetrazine may have a higher risk of habit formation due to its schedule III classification, while phentermine is a schedule IV drug with a lower chance of causing dependence.
  • Brand Names: Phendimetrazine is a generic medication also known by brand names such as Bontril, Adipost, Anorex-SR, Appecon, Bontril PDM, and Bontril Slow Release. Phentermine is also available under brand names like Adipex-P and Lomaira.

Both phendimetrazine and phentermine are FDA-approved medications used as appetite suppressants, and the amount of weight that can be lost varies from person to person. It is essential to seek professional medical advice when determining the best option for your condition.

Comparative Table: Phentermine vs Phendimetrazine Tartrate

Phentermine and phendimetrazine tartrate are both appetite suppressants and stimulants used for weight loss, but they have some differences in their available forms, dosages, and classification as controlled substances. Here is a table comparing the two medications:

Characteristic Phentermine Phendimetrazine Tartrate
Controlled Substance Schedule IV Schedule III
Available Forms Oral tablet, capsule, extended-release capsule, orally disintegrating tablet 35 mg tablet, 105 mg extended-release capsule
Usual Dosage 15 to 37.5 mg, depending on the dosage form 35 mg two to three times daily one hour before meals
Effectiveness Effective in reducing weight More effective at weight loss than phentermine
Stimulant Properties Chemically similar to amphetamines Has more qualities like amphetamines, more stimulating than phentermine
Half-Life 20 hours 3.7 hours
Brand Names Adipex-P, Atti-Plex P, Lomaira Adipost, Anorex-SR, Appecon, Bontril PDM, Fendique ER, Prelu-2 TR

Both medications are chemically similar to amphetamines and carry a risk of abuse due to their stimulant properties. They are typically prescribed for short-term use and should be taken under medical supervision.