What is the Difference Between Panadol and Aspirin?

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The main difference between Panadol (paracetamol) and aspirin lies in their chemical composition and mechanism of action for pain relief.

Aspirin, also known as acetylsalicylic acid, is a non-steroidal anti-inflammatory drug (NSAID) that contains salicylate and works by reducing pain and inflammation. It is used to treat various conditions, including pain, inflammation, fever, and even to thin the blood.

On the other hand, paracetamol is an analgesic that targets the prostaglandins found in the brain, reducing or completely preventing their production. Prostaglandins are chemicals that cause pain and inflammation. Paracetamol is typically used for mild to moderate pain, such as headaches, toothache, muscle and joint pains, and menstrual pain.

While both aspirin and paracetamol are effective painkillers, they have some differences in their efficacy for specific types of pain:

  • Aspirin may be better for period pain or migraines, although it can make heavy periods heavier.
  • Paracetamol may be better for headaches, toothache, sprains, and stomach ache.
  • NSAIDs like ibuprofen are considered better than paracetamol for back pain.

It is essential to consider individual factors, such as medical history and potential interactions with other medications, when choosing between aspirin and paracetamol for pain relief. Always consult a healthcare professional for personalized advice on pain management.

Comparative Table: Panadol vs Aspirin

Here is a table comparing the differences between Panadol (paracetamol) and Aspirin:

Property Panadol (Paracetamol) Aspirin
Classification Non-opioid (non-narcotic) painkiller and fever reducer Non-steroidal anti-inflammatory drug (NSAID)
Uses Relieves pain and fever, typically for conditions like headaches, sore throat, toothache, and period pain Relieves pain, inflammation, and helps thin the blood. Used for conditions like rheumatic and muscular pain, sprains, backache, and flu-like symptoms
Dosage Adult dose: 1-2 tablets (500-1000 mg) every 4-6 hours Adult dose: 300-900 mg every 4-6 hours, maximum 4g daily
Side Effects Higher dosages may cause stomach irritation Can cause stomach ulcers, bleeding disorders, and may interact with other medications, vitamins, herbals, or dietary supplements
Pregnancy Category Not classified (Category C) Risk cannot be ruled out (Category C)
Drug Interactions 115 known drug interactions 342 known drug interactions
First Approval Date N/A June 25, 1965

Please note that the information provided is for general educational purposes and should not be used as a substitute for professional medical advice. Always consult your healthcare provider before starting any new medication or if you have concerns about drug interactions or side effects.