What is the Difference Between Operon and Cistron?

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The main difference between an operon and a cistron lies in their structure and function. Here are the key differences:

  1. Structure: An operon is a functional unit of DNA that contains a group of genes under the control of a single promoter, while a cistron is a segment of DNA that encodes a single protein. An operon contains multiple structural genes (cistrons).
  2. Function: An operon is a regulatory system that allows for the coordinated expression of multiple genes, saving energy by transcribing multiple proteins at once. In contrast, a cistron is an individual gene that translates into a functional polypeptide.
  3. Transcription: An operon produces a polycistronic mRNA, which can be translated into separate proteins, while a cistron produces a monocistronic mRNA in eukaryotes, translating into a single protein.

In summary, an operon is a regulatory system consisting of multiple genes tightly regulated by a single promoter, while a cistron refers to a single gene and its associated functions. Operons are found primarily in bacteria and archaea, while cistrons are used as an alternative name for genes in all organisms.

Comparative Table: Operon vs Cistron

Here is a table comparing the differences between an operon and a cistron:

Feature Operon Cistron
Definition An operon contains multiple structural genes (cistrons) under the control of a single promoter and operator. A cistron is an alternative name for a single gene, consisting of one gene.
Nature of mRNA An operon produces a polycistronic mRNA. A cistron produces a monocistronic mRNA in eukaryotes.
Composition An operon is composed of structural genes, operator, and promoter regions. A cistron is composed of exons and introns.
Function Operons are used in metabolic pathways, such as synthesis of amino acids. Cistron codes for a single protein.

In summary, an operon is a regulatory system that consists of multiple structural genes (cistrons) under the influence of a single promoter and operator, while a cistron refers to a single gene with its associated regulatory elements.