What is the Difference Between Novarel and Pregnyl?

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Novarel and Pregnyl are two medications containing the hormone human chorionic gonadotropin (HCG), which is produced by the human placenta. Both medications are used to treat different conditions, and their main differences are as follows:

  • Target Population: Novarel mainly targets males, particularly young males with prepubertal cryptorchidism, while Pregnyl mainly targets women to stimulate ovulation and induce pregnancy.
  • Dosage: Novarel usually starts at a dosage of 4,000 USP units and reduces to 500-1,000 USP units, while Pregnyl typically starts from 500-1,000 USP units and increases up to 4,000 USP units.

Despite these differences, both Novarel and Pregnyl are used to induce ovulation in ovarian stimulation cycles for in vitro fertilization (IUI). There are no major differences in the clinical effects of these two products, and they are usually injected subcutaneously or intramuscularly. Some side effects of these medications include headache, restlessness, fatigue, edema, hypersensitivity reactions, depression, and pain at the site of injection. Dosages for both medications depend on age, weight, medical condition, and response to treatment.

Comparative Table: Novarel vs Pregnyl

Novarel and Pregnyl are both medications containing the hormone HCG (human chorionic gonadotropin), which is produced by the human placenta. However, they are used for different purposes and have some differences in their dosages. Here is a comparison table between the two medications:

Parameter Novarel Pregnyl
Uses Treats young males with prepubertal cryptorchidism Mainly treats females to stimulate ovulation and induce pregnancy
Dosage Progression Starts at 4000 USP units, then reduces to 500-1000 USP units Starts at 500-1000 USP units, then increases up to 4000 USP units
Target Gender Mainly males Mainly females

Both Novarel and Pregnyl are given as injections into a muscle. They work by simulating the body's natural LH surge, causing the final maturation of the eggs, and are expected to trigger ovulation 38-40 hours after administration.