What is the Difference Between Myokymia and Fasciculations?

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Myokymia and fasciculations are both types of muscle twitches, but they have distinct characteristics:

Myokymia:

  • Rhythmic and slower contractions in muscles at the same place.
  • Specifically involves the twitching of the eyelid.
  • Common in students, occurring in 40% of medical students.
  • Can be treated with rest, reducing stress, and in some cases, Botulinum toxin injections.

Fasciculations:

  • Non-rhythmic and faster contractions in muscles at the same place or different locations.
  • Visible and spontaneous muscular contractions that occur but do not result in the movement of a limb.
  • Occur in about 70% of all people.
  • Caused by stress, caffeine, poison, strenuous exercise, and ALS.
  • Can be treated with rest, reducing stress, and cutting back on caffeine.

Both conditions can be diagnosed through physical examination, blood tests, and nerve conduction tests. In some cases, treating underlying conditions like ALS, counseling, stretching exercises, massage, and immunosuppressive therapy with prednisone may be used to reduce cramps.

Comparative Table: Myokymia vs Fasciculations

Myokymia and fasciculations are two different types of muscle twitching conditions. Here is a table summarizing the differences between them:

Feature Myokymia Fasciculations
Definition Involuntary spontaneous twitching of muscles or bundles within a muscle, commonly used to describe involuntary eyelid contraction Visible and spontaneous muscular contractions that occur but are not powerful enough to move a joint
Contraction Type Rhythmic and slower contractions in muscles at the same place Non-rhythmic and faster contractions in muscles at the same place or different locations
Location Mainly occurs in areas such as the eyelid, face, and limbs Mainly occurs in areas such as limbs and the tongue
Causes Stress, anxiety, lack of sleep, alcohol intake, and other factors Stress, physical activity, too much caffeine, and poisons (insecticides)
Prevalence Common in students, occurring in 40% of medical students Occurs in about 70% of all people
Treatment Usually no particular treatment is required, may subside if the underlying etiology is removed Rest, decrease stress and worry, cut back on caffeine, and in some cases, Botulinum toxin injections

In summary, myokymia is characterized by rhythmic and slower contractions in muscles, typically occurring in the eyelids, face, and limbs, while fasciculations are non-rhythmic and faster contractions in muscles, mainly occurring in the limbs and tongue.