What is the Difference Between Mobitz 1 and 2?

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Mobitz type 1 and type 2 are both subtypes of second-degree atrioventricular (AV) block, which is an irregular cardiac rhythm reflecting a conduction block in the electrical system of the heart. The main differences between Mobitz type 1 and type 2 are:

  1. Gradual prolongation of PR intervals: In Mobitz type 1, the PR interval gradually lengthens before a block occurs, while in Mobitz type 2, the PR intervals are constant and not prolonged.
  2. Prognosis: Mobitz type 1 is generally benign and reflects a block at the AV node, often indicating a better prognosis. In contrast, Mobitz type 2 reflects a block after the AV node, either at the bundle of His or its branches, and often results in a poorer prognosis, as it has a higher risk of progressing to third-degree AV block.
  3. Causes: Mobitz type 1 can occur as a result of reversible conduction block caused by metabolic factors, while Mobitz type 2 is typically associated with a more serious underlying issue, such as heart disease.

To differentiate between Mobitz type 1 and type 2, if there is a gradual prolongation of PR intervals before a block, Mobitz type 1 should be diagnosed. If the PR intervals are constant but varying, Mobitz type 1 should still be diagnosed. If the PR intervals are constant and not prolonged, Mobitz type 2 should be diagnosed.

Comparative Table: Mobitz 1 vs 2

Mobitz 1 and Mobitz 2 are the two primary types of second-degree heart block, which is a condition where there is a delay in the transmission of impulses through the atrioventricular (AV) node. The main difference between Mobitz 1 and Mobitz 2 lies in the behavior of the PR interval and the block's prognosis. Here is a comparison table of the two types:

Feature Mobitz 1 Mobitz 2
PR Interval Behavior Gradual lengthening of the PR interval before a block Constant PR interval before blocks occur
Prognosis Benign and usually indicates AV node obstruction Worse prognosis, often manifests a block after the AV node, and more likely to progress to a third-degree block
ECG Characteristics Irregular, non-conducted P waves Occurrence of irregular, non-conducted P waves
Treatment May not require treatment unless symptomatic Artificial pacemaker may be necessary

In Mobitz 1, the PR interval progressively lengthens with each beat until the atrial impulse is not conducted, and AV nodal conduction resumes with the next beat. In contrast, Mobitz 2 has a constant PR interval, and beats are intermittently non-conducted, usually in a repeating cycle of every 3rd (3:1 block) or 4th (4:1 block) P wave. Mobitz 1 is generally considered benign and may indicate AV node obstruction, while Mobitz 2 has a worse prognosis and is more likely to progress to a third-degree block.