What is the Difference Between Methylphenidate and Dexmethylphenidate?

🆚 Go to Comparative Table 🆚

Methylphenidate and dexmethylphenidate are both stimulant medications used to treat attention deficit hyperactivity disorder (ADHD), but they have some differences in their composition and potency. Here are the key differences between the two:

  1. Active Ingredient: Methylphenidate (Ritalin) contains two types of methylphenidate drugs, while dexmethylphenidate (Focalin) only contains the most potent of these types of methylphenidate.
  2. Potency: Dexmethylphenidate (Focalin) is twice as potent as methylphenidate (Ritalin).
  3. Starting Dose: In children, the starting dose of dexmethylphenidate is one-half of the methylphenidate dose (0.15 mg/kg in the morning, rounded to the nearest 2.5-mg tablet).
  4. Duration: Studies comparing dexmethylphenidate and methylphenidate have concluded that both are effective in treating ADHD, but dexmethylphenidate has a longer duration.
  5. Side Effects: Both medications have similar potential side effects, but individuals may respond differently.

The choice between methylphenidate and dexmethylphenidate depends on individual responses and specific treatment needs. Both medications are prescribed to treat ADHD in children over 6 years old, adolescents, and adults.

Comparative Table: Methylphenidate vs Dexmethylphenidate

Methylphenidate and Dexmethylphenidate are both used to treat ADHD, but they have some differences in their potency and side effects. Here is a table comparing the two:

Feature Methylphenidate Dexmethylphenidate
Potency Less potent than dexmethylphenidate Twice as potent as methylphenidate
Dosages Requires higher doses Requires lower doses
Side Effects Similar side effects to dexmethylphenidate, but individuals may respond differently Same side effects as methylphenidate, but individuals may respond differently
Active Ingredient(s) Contains two types of methylphenidate drugs Contains only the most potent type of methylphenidate drug
Brand Names Ritalin, Concerta Focalin, Focalin XR

Both medications are effective in treating ADHD, but the choice between them depends on individual responses and specific needs. Dexmethylphenidate is more potent than methylphenidate, which means it may be more effective at lower doses. However, both medications have similar side effects, and individuals may respond differently to each.