What is the Difference Between Magnesium Oxide and Magnesium Glycinate?

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The main difference between magnesium oxide and magnesium glycinate lies in their molecular structure and bioavailability. Here are the key differences:

  1. Form: Magnesium oxide is an inorganic compound, while magnesium glycinate is an organic compound.
  2. Content & Absorption: Magnesium oxide has a high magnesium content per unit volume, but its absorption by the body is poor. In contrast, magnesium glycinate has lower magnesium content per unit volume, but its absorption by the body is high.
  3. Composition: Magnesium oxide mainly consists of magnesium and oxygen, while magnesium glycinate consists of magnesium, glycine, and other chemical components.
  4. Bioavailability: Magnesium oxide has a low absorption rate of around 4%, while magnesium glycinate has a much higher absorption rate, making it a more effective form for raising magnesium levels in the body.
  5. Uses: Magnesium oxide is commonly used for constipation or heartburn, while magnesium glycinate is used as a supplement for magnesium, which is an essential mineral that plays a crucial role in various physiological functions.
  6. Additional Benefits: The presence of glycine in magnesium glycinate makes it more beneficial, as it has calming effects on the nervous system and is used to manage stress and promote healthy sleep patterns.

In summary, while magnesium oxide has a higher elemental magnesium content, its low absorption rate makes it less effective compared to magnesium glycinate, which has a higher absorption rate and additional benefits such as calming effects on the nervous system.

Comparative Table: Magnesium Oxide vs Magnesium Glycinate

Magnesium oxide and magnesium glycinate are two different forms of magnesium supplements. Here is a comparison table highlighting their differences:

Property Magnesium Oxide Magnesium Glycinate
Chemical Formula MgO C4H8MgN2O4
Elemental Magnesium Content High (around 60%) Lower (around 14.1%)
Absorption Rate Poor (around 4%) High (around 18.8%)
Bioavailability Low High
Common Uses Constipation, heartburn Raising magnesium levels, promoting relaxation, supporting sleep cycle
Side Effects Can cause stomach discomfort or diarrhea Generally well-tolerated, gentle on the digestive system

Magnesium oxide has a higher magnesium content but a lower absorption rate compared to magnesium glycinate. This means that while magnesium oxide may seem like a more affordable option, its low bioavailability may not deliver the desired results. Magnesium glycinate, on the other hand, has a higher absorption rate and is gentler on the digestive system, making it a popular choice for those with sensitive stomachs or bowel issues. Additionally, the glycine in magnesium glycinate may provide additional benefits, such as promoting relaxation and supporting a healthy sleep cycle.