What is the Difference Between Magnesium Citrate Malate and Glycinate?

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Magnesium citrate and magnesium glycinate are two different forms of magnesium supplements, and their key differences lie in their specific benefits and absorption.

Magnesium Citrate:

  • Bound with citric acid, making it more easily absorbed in the digestive tract.
  • Often used to replenish low magnesium levels and as a natural laxative to treat constipation.
  • Sometimes marketed as a calming agent to help relieve symptoms associated with depression, but more research is needed on these uses.

Magnesium Glycinate:

  • Formed from elemental magnesium and the amino acid glycine.
  • Often used for its calming effects to treat anxiety, depression, and insomnia.
  • Contains 14.1% elemental magnesium by mass, which is lower than magnesium citrate's bioavailability.

While both forms of magnesium can be effective, the choice between magnesium citrate and magnesium glycinate depends on your health needs and goals. Magnesium citrate is a more common choice for maintaining magnesium levels for general whole-body health, while magnesium glycinate is preferred for its calming effects. It is essential to work with a functional medicine practitioner or healthcare professional to optimize your magnesium status and choose the right supplement based on your individual needs.

Comparative Table: Magnesium Citrate Malate vs Glycinate

Magnesium Citrate Malate and Magnesium Glycinate are two different forms of magnesium supplements. Here is a table comparing their differences:

Property Magnesium Citrate Malate Magnesium Glycinate
Composition Magnesium combined with citric and malic acids Magnesium combined with the amino acid glycine
Absorption Very well absorbed in the digestive tract Highly bioavailable, second only to magnesium citrate
Effects May have a mild laxative effect Known for calming effects, used to treat anxiety, depression, and insomnia
Energy-related benefits May aid in energy production due to the presence of malic acid No specific energy-related benefits
Potential side effects Diarrhea due to its natural laxative effect Limited research on potential side effects, but generally well-tolerated

Both magnesium citrate malate and magnesium glycinate are highly bioavailable and easily absorbed in the body. However, they differ in their effects and potential side effects. Magnesium citrate malate may have a laxative effect and potentially provide energy-related benefits due to the presence of malic acid. On the other hand, magnesium glycinate is known for its calming effects and is used to treat anxiety, depression, and insomnia. It is essential to consult a healthcare professional before choosing a magnesium supplement to ensure it meets your specific needs and does not cause any adverse side effects.