What is the Difference Between Lexapro and Prozac (Escitalopram and Fluoxetine)?

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Lexapro and Prozac are both selective serotonin reuptake inhibitors (SSRIs) used to treat mental health conditions such as depression and anxiety. They have some differences in their chemical composition, side effects, and specific uses. Here are the main differences between Lexapro and Prozac:

  1. Chemical Composition: Lexapro contains escitalopram, a refined version of citalopram, while Prozac contains fluoxetine, the first SSRI.
  2. Side Effects: Both medications have similar side effects, such as nausea, sexual dysfunction, dry mouth, headache, insomnia, and diarrhea. However, Lexapro's side effects tend to be more mild.
  3. Specific Uses: Lexapro is FDA-approved to treat anxiety, while Prozac is sometimes used off-label for anxiety. Prozac has a wider range of applications, including bulimia nervosa and premenstrual dysphoric disorder.
  4. Dosage Forms: Lexapro is available in tablet form in strengths of 5 mg, 10 mg, and 20 mg, as well as in liquid form at 1 mg/ml. Prozac is available in capsule form at strengths of 10 mg, 20 mg, and 40 mg, and in liquid form at 20 mg/5 ml. There is also a delayed-release "weekly" form of Prozac available at a strength of 90 mg.

Ultimately, the choice between Lexapro and Prozac depends on individual factors, such as the specific mental health condition being treated, side effect profile, and dosage preferences. It is essential to consult with a healthcare professional to determine the most appropriate medication for your needs.

Comparative Table: Lexapro vs Prozac (Escitalopram vs Fluoxetine)

Lexapro (escitalopram) and Prozac (fluoxetine) are both selective serotonin reuptake inhibitors (SSRIs) used to treat depression, anxiety, and other mental health conditions. Here is a table comparing the differences and similarities between the two medications:

Key Components Prozac Lexapro
Generic Name Fluoxetine Escitalopram
Forms Tablet, Capsule, Solution Tablet, Solution
Side Effects Nausea (22%), Headache (21%), Diarrhea (11%), Dry Mouth (9%), Sweating (7%), Insomnia (19%), Dizziness (9%), Nervousness (13%), Decreased Libido (4%) Nausea (15%), Headache (24%), Diarrhea (8%), Dry Mouth (6%), Sweating (5%), Insomnia (9%), Dizziness (5%), Nervousness (0%), Decreased Libido (3%)

Both medications are effective in relieving symptoms of depression and anxiety, but they may cause similar side effects, such as nausea, headache, diarrhea, dry mouth, sweating, insomnia, dizziness, and nervousness. Lexapro may have a lower side effect burden. Your doctor can help you determine which medication is better suited for your individual needs.