What is the Difference Between LDH and Lactic Acid?

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LDH (lactate dehydrogenase) and lactic acid are two different compounds involved in the cellular respiration process. The main differences between them are:

  1. Function: LDH is an enzyme that catalyzes the interconversion of lactate to pyruvate, while lactic acid is an organic acid produced when glucose is broken down to generate ATP in anaerobic conditions.
  2. Structure: LDH is a tetrameric enzyme with a molecular weight of 144,000 g/mol, while lactic acid has a molecular weight of 90.08 g/mol.
  3. Formation: LDH is present in almost all body tissues and is involved in the anaerobic metabolic pathway, producing lactic acid as an end product through a fermentation reaction.
  4. Usage: LDH is used as a marker enzyme to predict mortality in various conditions such as ARDS, serious COVID-19, and cancer patients. Lactic acid can affect the immune system, act as a signaling molecule, and regulate pH. It is also used in food manufacturing to increase shelf life and treat hyperpigmentation, age spots, and other factors that contribute to a dull and uneven skin complexion.

In summary, LDH is an enzyme involved in the anaerobic metabolic pathway that produces lactic acid as an end product, while lactic acid is an organic acid generated in anaerobic conditions.

Comparative Table: LDH vs Lactic Acid

LDH (lactate dehydrogenase) and lactic acid are two compounds involved in anaerobic respiration. Here is a table summarizing their differences:

Feature LDH Lactic Acid
Definition LDH is an enzyme that plays a crucial role in cellular respiration, catalyzing the interconversion of lactate to pyruvate. Lactic acid is an organic acid produced when glucose is broken down to generate ATP in the absence of oxygen.
Role in Respiration LDH is involved in the conversion of pyruvate to lactate, which allows for anaerobic ATP production. Lactic acid is formed from the breakdown of pyruvate in anaerobic conditions and contributes to anaerobic ATP production.
Industrial Applications LDH has industrial applications in the food industry, where it is used for processing bakery products, desserts, olives, and jams, as well as in cosmetics for treating hyperpigmentation and age spots. Lactic acid is used in the food industry as an acidulant and flavor enhancer, as well as in the production of polylactic acid for biodegradable products.

Both LDH and lactic acid are involved in anaerobic respiration and play a pivotal role in cellular respiration. They both contribute to ATP production without oxygen, but they have different functions and industrial applications.