What is the Difference Between Isoflurane and Sevoflurane?

Isoflurane and sevoflurane are both inhaled anesthetics used for general anesthesia during surgeries. They have some differences in terms of their effects on patients and costs. Here are the main differences between the two:

1. Emergence and recovery: Sevoflurane has been found to have a quicker emergence and earlier discharge from the post-anesthesia care unit (PACU) compared to isoflurane.
2. Airway hyperreactivity: Isoflurane has a higher incidence of mild airway hyperreactivity compared to sevoflurane.
3. Cost: Isoflurane is less costly than sevoflurane.
4. Induction: Sevoflurane induction tends to be smoother and is associated with fewer complications than isoflurane induction.
5. Pain scores and recovery: Sevoflurane patients had higher pain scores, but there was no evidence of emergence delirium. Recovery after sevoflurane is subjectively more rapid.

Despite these differences, both isoflurane and sevoflurane are considered suitable for day care anesthesia. The choice between the two anesthetics depends on the specific needs of the patient and the surgical procedure being performed.

Comparative Table: Isoflurane vs Sevoflurane

Here is a table comparing the differences between isoflurane and sevoflurane:

Both isoflurane and sevoflurane are maintenance anesthetic agents used in day care surgeries. They have some differences in their effects on blood pressure and airway hyperreactivity, but their overall incidence of nausea, vomiting, and postoperative analgesia requirements are comparable. Additionally, isoflurane is less costly than sevoflurane.