What is the Difference Between Hypercholesterolemia and Dyslipidemia?

🆚 Go to Comparative Table 🆚

Hypercholesterolemia and dyslipidemia are both conditions related to abnormal blood lipid levels, but they have distinct differences.

  • Hypercholesterolemia is a specific type of dyslipidemia characterized by elevated levels of low-density lipoprotein cholesterol (LDL-C) or non-high-density lipoprotein cholesterol (HDL-C). It is an important risk factor for atherosclerotic cardiovascular diseases, including cerebrovascular disease, coronary heart disease, and peripheral arterial disease.
  • Dyslipidemia is an umbrella term that encompasses various disorders causing high lipid levels in the blood, including elevated triglycerides, low levels of HDL-C, and qualitative lipid abnormalities. It can be classified as serum total cholesterol (TC), LDL-C, triglycerides, apolipoprotein B, or lipoprotein(a) concentrations above the 90th percentile, or HDL-C or apolipoprotein A-I concentrations below the 10th percentile for the general population.

In summary, the main differences between hypercholesterolemia and dyslipidemia are:

  • Hypercholesterolemia specifically refers to elevated levels of LDL-C or non-HDL-C, while dyslipidemia is a broader term that includes various imbalances in blood lipid levels.
  • Hypercholesterolemia is a type of dyslipidemia, focusing on cholesterol levels, whereas dyslipidemia covers a wider range of lipid imbalances, including triglycerides and HDL-C.

Both conditions are often asymptomatic and are typically discovered during routine blood screenings. They can be managed through medications and lifestyle changes, such as maintaining a moderate weight, eating a balanced diet, and exercising regularly.

Comparative Table: Hypercholesterolemia vs Dyslipidemia

Hypercholesterolemia and dyslipidemia are both conditions related to abnormal levels of lipids in the blood, but they have distinct differences. Here is a table comparing the two:

Feature Hypercholesterolemia Dyslipidemia
Definition Refers specifically to elevated levels of LDL cholesterol An umbrella term that describes an imbalance of lipids in the body, including LDL, HDL, and triglycerides
Subtypes Does not include other types of lipid imbalances Includes various subtypes, such as hyperlipidemia (high lipid levels), hypertriglyceridemia (high triglyceride levels), and others
Symptoms Usually no symptoms, typically discovered during routine blood screenings May present with symptoms related to high lipid levels, such as xanthomas (fatty deposits under the skin) or pancreatitis (inflammation of the pancreas)
Causes Can be due to genetic factors, such as familial hypercholesterolemia, or lifestyle factors, such as diet and lack of exercise Can be due to various factors, including genetic predisposition, hypothyroidism, alcoholism, obesity, and more
Treatment Often managed with lifestyle changes, medications, or a combination of both Managed through lifestyle changes, medications, and other treatments, depending on the specific type and cause of dyslipidemia

In summary, hypercholesterolemia is a specific type of dyslipidemia that focuses on elevated LDL cholesterol levels, while dyslipidemia is a broader term encompassing various imbalances in lipid levels. Both conditions can be managed through lifestyle changes and medications, depending on the severity and specific cause of the lipid abnormalities.