What is the Difference Between Hendravirus and Nipahvirus?

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Hendravirus and Nipahvirus are both members of the Paramyxoviridae family and cause respiratory and nervous system diseases. They have some differences in terms of transmission, symptoms, and effects on humans and animals:

  1. Transmission: Close contact with tissues or bodily fluids of infected animals is required for infection. While Hendra virus is not very contagious, Nipah virus appears to be much more easily transmitted.
  2. Symptoms: In humans, both viruses cause flu-like symptoms, including fever and muscle soreness. They can also cause headache, drowsiness, and disorientation. In some cases, infection can lead to coma and death. In animals, horses infected with Hendra virus usually have an acute fever and appear sick.
  3. Geographical distribution: Hendra virus is endemic in Australia, while Nipah virus has been found in Southeast Asia and Australia.
  4. Natural reservoir: Both viruses have flying foxes (pteropid fruit bats) as their natural reservoir.
  5. Incubation period: The incubation period for Hendra virus is 9-16 days, while for Nipah virus, it is 5-14 days.
  6. Mortality rate: The fatality rate for Nipah virus infection in the India outbreak approached 70%.
  7. Viability: Both Hendra and Nipah viruses have similar susceptibility to common disinfectants, such as 70% ethanol, 1% sodium hypochlorite, and 2% glutaraldehyde.

Despite their differences, both viruses are highly pathogenic and have recently emerged from flying foxes to cause serious disease outbreaks in humans and animals.

Comparative Table: Hendravirus vs Nipahvirus

Hendra Virus (HeV) and Nipah Virus (NiV) are both highly pathogenic paramyxoviruses that have recently emerged from flying foxes, causing serious disease outbreaks in humans and animals. Here is a table highlighting the differences between Hendravirus and Nipahvirus:

Feature Hendravirus Nipahvirus
Genus Henipavirus Henipavirus
Discovery 1994 in Australia 1999 in Malaysia, Singapore, and Bangladesh
Reservoir Flying foxes Flying foxes
Transmission Close contact with tissues or bodily fluids of infected animals Close contact with tissues or bodily fluids of infected animals
Disease Symptoms Respiratory and neurological disease in horses and humans Encephalitis and respiratory disease in pig farmers, with more than 200 illnesses and 40% involving serious neurologic disease and death
Diagnosis Blood test to detect the body's immune response to infection; virus isolation from clinical samples Blood test to detect the body's immune response to infection; virus isolation from clinical samples
Treatment No specific treatment besides supportive care No specific treatment besides supportive care
Prevention Avoid contact with infected animals and their body fluids Avoid contact with infected animals and their body fluids

Both viruses are members of the Paramyxoviridae family and cause respiratory and nervous system diseases in animals and humans. They are bat-borne zoonotic viruses, meaning they can be transmitted from animals to humans. Despite their distinct genetic and biological properties, they share similarities in their transmission, diagnosis, and treatment.