What is the Difference Between HDL and LDL Cholesterol?

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The main difference between HDL and LDL cholesterol lies in their functions and effects on the body. HDL (high-density lipoprotein) and LDL (low-density lipoprotein) are two types of cholesterol that carry cholesterol to and from cells. Here are the key differences between HDL and LDL cholesterol:

  • Function: HDL is considered "good" cholesterol because it transports cholesterol to the liver, where it can be removed from the bloodstream before it builds up in the arteries. LDL, on the other hand, is considered "bad" cholesterol because it carries cholesterol to the arteries, where it can collect in the artery walls and contribute to plaque formation, known as atherosclerosis.
  • Health Effects: High levels of HDL cholesterol can lower the risk of heart disease and stroke. In contrast, high levels of LDL cholesterol raise the risk of heart disease and stroke by contributing to the buildup of plaque in the arteries. This plaque buildup can lead to decreased blood flow to the heart muscle (coronary artery disease) or leg muscles (peripheral artery disease) or abrupt closure of an artery in the heart or brain, leading to a heart attack or stroke.
  • Goal Levels: A healthy goal for HDL cholesterol is higher than 55 mg/dL for women and 45 mg/dL for men. For LDL cholesterol, an LDL count of 100 or less is considered healthy.

Comparative Table: HDL vs LDL Cholesterol

HDL and LDL cholesterol are two main types of cholesterol that differ in their functions and effects on the body. Here is a table summarizing the differences between HDL and LDL cholesterol:

Feature HDL Cholesterol (Good) LDL Cholesterol (Bad)
Function Transports cholesterol to the liver to be released, helping rid the body of excess cholesterol Collects in the walls of blood vessels, narrowing them and increasing the risk of heart attack and stroke
Size HDL particles are smaller, measuring 5-12 nanometers LDL particles are larger, measuring 18-25 nanometers
Health High HDL levels are desirable, with at least 55 mg/dL for females and 45 mg/dL for males High LDL levels are undesirable, with a recommended maximum of 130 mg/dL for individuals without heart disease, blood vessel disease, or diabetes, and no more than 100 mg/dL for those with these conditions

In summary, HDL cholesterol is considered "good" because it helps remove excess cholesterol from the body, while LDL cholesterol is considered "bad" because it collects in blood vessels and increases the risk of heart attack and stroke.