What is the Difference Between G1 and G2 Phase of Cell Cycle?

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The G1 and G2 phases are part of the cell cycle, which is divided into interphase (G1, S, and G2 phases) and the mitotic phase (mitosis and cytokinesis). Here are the main differences between the G1 and G2 phases:

G1 Phase:

  • Occurs after cell division in mitosis and before DNA replication in the S phase.
  • The cell grows physically, increasing its volume and the volume of its organelles.
  • Protein synthesis occurs during the G1 phase.

G2 Phase:

  • Occurs after the S phase, during which DNA is replicated.
  • The cell undergoes further growth and protein synthesis.
  • Energy is replenished, new proteins are synthesized, and additional growth occurs in the G2 phase.

In summary, the G1 phase is focused on cell growth and preparation for DNA replication, while the G2 phase involves further growth, protein synthesis, and preparation for cell division.

Comparative Table: G1 vs G2 Phase of Cell Cycle

The G1 and G2 phases are part of the interphase in the cell cycle, which is divided into G1, S, and G2 phases. Here is a table highlighting the differences between the G1 and G2 phases:

Feature G1 Phase G2 Phase
Definition G1 phase is the first cell growth phase of the interphase of the cell cycle, also referred to as Gap 1 stage. G2 phase is the final substage of interphase and is considered to be an important phase in the cell cycle.
Duration Longer than G2 phase. Shorter than G1 phase.
Cell Growth The cell increases its size due to extensive synthesis of proteins and RNA. The cell grows more, synthesizes proteins and organelles, and reorganizes cell contents.
DNA Replication DNA replication does not occur in G1 phase. DNA replication has already occurred in the S phase before G2 phase.

Both phases are crucial for the cell's growth and preparation for division. The G1 phase involves significant development processes within the cell, while the G2 phase is shorter and focuses on organizing the cell's contents in preparation for mitosis.