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Guilherme Mazui

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What is the Difference Between FSH and LH?

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FSH (follicle-stimulating hormone) and LH (luteinizing hormone) are both gonadotropins that play crucial roles in regulating the function of the gonads, which are the testes in males and the ovaries in females. They have distinct roles and effects in both males and females:

FSH:

  • In females, FSH stimulates the growth and development of ovarian follicles and regulates the production of estrogen and progesterone.
  • In males, FSH stimulates the Sertoli cells to produce androgen-binding protein (ABP), which in turn stimulates spermatogenesis.

LH:

  • In females, LH triggers ovulation and stimulates the production of estrogen and progesterone.
  • In males, LH stimulates the Leydig cells to produce testosterone.

In both males and females, the secretion of FSH and LH is regulated by gonadotropin-releasing hormone (GnRH). While both hormones share some similarities, they have distinct roles in the reproductive system, and their synergistic actions are essential for optimal follicle development and ovulation.

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  • What is the Difference Between FSH and LH?
  • Comparative Table: FSH vs LH

    • Comparative Table: FSH vs LH

    Here is a table comparing the differences between Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH):

    Feature FSH LH
    Alternative Name Follitropin Luveris
    Hormone Type Polypeptide hormone Heterodimeric glycoprotein
    Secreted by Gonadotropic cells of the anterior pituitary Gonadotropic cells of the anterior pituitary
    Reproductive Role in Men Stimulates Sertoli cells, resulting in spermatogenesis Stimulates interstitial Leydig cells, causing them to produce testosterone
    Reproductive Role in Women Stimulates the growth of ovarian follicles and steroidogenesis Triggers ovulation through a mid-cycle surge; acts on Leydig cells to stimulate androgen production
    Effect on LH/FSH Ratio FSH levels usually increase during menopause due to ovarian resistance LH/FSH ratio can be used to diagnose primary and secondary hypogonadism

    Both FSH and LH are gonadotropic hormones synthesized and secreted by the gonadotropic cells of the anterior pituitary. They play important roles in regulating reproduction processes in both men and women.

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    Guilherme Mazui

    Guilherme Mazui is graduated in journalism from the Federal University of Minas Gerais (UFMG) and a master's degree in Communication from the University of São Paulo (USP). In addition, he has experience in advertising writing and has worked as a content editor in several companies.