What is the Difference Between Formoterol and Albuterol?

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Formoterol and albuterol are both β2-agonists used in the treatment of asthma and other lung-related diseases, but they have different durations of action and some differences in their effects.

  • Formoterol is a long-acting β2-agonist with a duration of action of around 12 hours. It is used for managing asthma and chronic obstructive pulmonary disease (COPD).
  • Albuterol is a short-acting β2-agonist with a duration of action ranging from 4 to 6 hours. It is commonly used as a rescue inhaler to provide rapid relief of asthma symptoms.

Studies have shown that formoterol has a rapid onset of action, comparable to albuterol, when administered via the Turbuhaler® system. Formoterol is considered as effective as albuterol in treating adults with mild to moderate asthma exacerbations in the acute care setting. However, albuterol is more commonly used as a rescue inhaler, providing quick relief of asthma symptoms.

In summary, the main difference between formoterol and albuterol is their duration of action, with formoterol being a long-acting β2-agonist and albuterol being a short-acting β2-agonist. Both medications are used to treat asthma and other lung-related diseases, but they may be used in different situations and for different purposes.

Comparative Table: Formoterol vs Albuterol

Formoterol and albuterol are both beta-2 agonists used for the treatment of asthma and other respiratory conditions. Here is a table comparing their differences:

Property Formoterol Albuterol
Duration of action 8-12 hours 6 hours
Onset of action Rapid Rapid
Delivery systems Turbuhaler® system, HFA Modulite inhaler Turbuhaler® system, metered-dose inhaler (MDI)
Usual dose 12 mcg 100 mcg (2 puffs at 50 mcg each)

Both formoterol and albuterol have a rapid onset of action. Formoterol has a longer duration of action, providing bronchodilation for 8 to 12 hours. Albuterol, on the other hand, has a duration of action of approximately 6 hours. Both medications can be administered via a Turbuhaler® system.