What is the Difference Between F Plasmid and R Plasmid?

🆚 Go to Comparative Table 🆚

The F plasmid and R plasmid are two types of plasmids, which are extrachromosomal circular DNA molecules that can replicate independently in bacteria. They differ in their functions and the genes they carry:

F Plasmid:

  1. Contains the fertility factor (F) necessary for conjugation, which is the process of transferring genetic materials between bacteria.
  2. Can form sex pili, which are structures used for conjugation.
  3. Transfer of the F plasmid typically occurs between F+ and F− cells, resulting in two F+ cells.

R Plasmid:

  1. Carries an antibiotic resistance gene or resistance factor, which can produce genes that either eliminate or modify antibiotics.
  2. Cannot form sex pili, but a bacterium with an F factor can transfer the resistance gene to another bacterium.

The spread of F plasmids is not a significant threat, whereas the spread of R plasmids is a concern for antibiotic treatments, as it can create antibiotic resistance in bacteria. It is common for plasmids to carry both the F factor and the R factor, facilitating the spread of antibiotic resistance among bacteria.

Comparative Table: F Plasmid vs R Plasmid

F Plasmid and R Plasmid are two types of extrachromosomal circular DNA found in bacteria that can replicate independently. They have distinct characteristics and roles:

F Plasmid R Plasmid
Contains fertility factor (F) necessary for conjugation Contains antibiotic resistance gene or resistance factor
Can form sex pilus and transfer genetic materials through conjugation Cannot form sex pilus, but can be transferred by a bacterium with an F factor
Exists in F+ and F- cells, with conjugation resulting in two F+ cells Presence in bacteria can lead to antibiotic resistance

F Plasmid, also known as the fertility plasmid, has the F factor that enables the transfer of genetic materials between bacteria through conjugation. This process typically involves an F+ bacterium transferring its genes to an F- bacterium, resulting in two F+ cells.

R Plasmid, on the other hand, carries antibiotic resistance genes or resistance factors. These factors can produce proteins that either eliminate or modify antibiotics, leading to antibiotic resistance in bacteria. The spread of antibiotic resistance is primarily due to the presence of R factors, and the growth of resistant bacteria is facilitated when bacteria possess both F and R factors.