What is the Difference Between Eugenol and Isoeugenol?

🆚 Go to Comparative Table 🆚

Eugenol and isoeugenol are both aromatic compounds found in essential oils, but they have different odors, structures, and biological activities. Here are the main differences between them:

  1. Odor: Eugenol has a clove-like odor, while isoeugenol has a floral odor.
  2. Structure: Eugenol is an allyl guaiacol substance with the chemical formula C10H12O2, while isoeugenol is a type of phenylpropene and a substituted guaiacol.
  3. Flavor Components: Eugenol is a flavor component of clove, while isoeugenol is a flavor component of nutmeg.
  4. Antioxidant Activities: Isoeugenol exhibits higher antioxidant activity than eugenol.
  5. DNA Damage Protective Effect: Isoeugenol has a stronger DNA damage protective effect than eugenol.
  6. Antibacterial Activity: Isoeugenol has a higher antibacterial activity than eugenol, and the antibacterial effects are significantly influenced by incubation time and concentration.

In summary, eugenol and isoeugenol are both aromatic compounds with different odors, structures, and biological activities. Isoeugenol generally exhibits higher antioxidant, DNA damage protective, and antibacterial activities compared to eugenol.

Comparative Table: Eugenol vs Isoeugenol

Eugenol and isoeugenol are both aromatic compounds found in essential oils, but they have distinct differences in their odor and structure. Here is a table comparing the two compounds:

Property Eugenol Isoeugenol
Chemical Formula C10H12O2 C10H12O2
Structure Allyl guaiacol with a clove-like odor Phenylpropene with a floral odor
Occurrence Found in high concentrations in clove bud oil and clove leaf oil, and also present in nutmeg, cinnamon, basil, and bay leaf essential oils Has a clove-like odor but is not as prevalent in essential oils as eugenol
Sources Mainly found in essential oils, such as clove, nutmeg, cinnamon, basil, and bay leaf Less common in essential oils, with its structure differing from eugenol through the replacement of the allyl substituent with a prop-1-enyl group

Despite having the same molecular formula, eugenol and isoeugenol have different odors and structures, with eugenol having a clove-like odor and isoeugenol having a floral odor.