What is the Difference Between Ephedrine and Pseudoephedrine?

Ephedrine and pseudoephedrine are both sympathomimetic amine compounds with similar properties, but they have some differences in their effects and uses. Here are the main differences between the two:

1. Action: Ephedrine is a mixed-acting sympathomimetic amine, while pseudoephedrine is an indirectly-acting sympathomimetic amine.
2. Bronchodilation: Both compounds act as bronchodilators, but pseudoephedrine has a considerably lesser effect compared to ephedrine.
3. Blood Pressure Increase: Both ephedrine and pseudoephedrine increase blood pressure, but pseudoephedrine is less effective in this regard.
4. Availability: Pseudoephedrine is available over the counter and can be taken orally, while ephedrine is a prescription drug and is administered nasally in France.
5. Brand Names: Some common brand names for ephedrine include Akovaz, Bronkaid Max, Corphedra, and Emerphed. Pseudoephedrine is found in several behind-the-counter medications, such as 12 Hour Decongestant, 12 Hour Nasal Decongestant, Afrinol, Allermed, Cenafed, and Children's Dimetapp Decongestant Infant.

In summary, ephedrine and pseudoephedrine are both sympathomimetic amines with some similar properties, but they differ in their effects on bronchodilation and blood pressure, as well as their availability and brand names.

Comparative Table: Ephedrine vs Pseudoephedrine

Ephedrine and pseudoephedrine are both sympathomimetic amine compounds with similar structures, but they have different properties and uses. Here is a table highlighting the differences between them:

Both ephedrine and pseudoephedrine act as bronchodilators and increase blood pressure, but pseudoephedrine has a considerably less powerful effect on both. Ephedrine is typically used to counteract orthostatic hypotension, while pseudoephedrine is used as a decongestant.