What is the Difference Between DMSO and MSM?

🆚 Go to Comparative Table 🆚

DMSO (Dimethyl Sulfoxide) and MSM (Methylsulfonylmethane) are two chemically related sulfur compounds that have been studied for their potential health benefits, particularly in the treatment of osteoarthritis. Here are the key differences between the two:

  • Form: DMSO is a liquid, while MSM is a crystalline, water-soluble powder.
  • Application: DMSO is typically used topically (applied to the skin), while MSM is sold as a dietary supplement, either alone or in combination with other ingredients such as glucosamine.
  • Natural Occurrence: MSM occurs naturally in the human body and is also found in protein-rich foods, such as eggs, meat, poultry, fish, and legumes, as well as in garlic, onions, Brussels sprouts, asparagus, kale, and wheat germ. DMSO, on the other hand, is a byproduct of paper making and is used as an industrial solvent.
  • Side Effects: MSM is generally well-tolerated and does not have significant side effects. However, some people may experience allergic reactions, digestive upsets, and skin rashes. DMSO, on the other hand, has side effects that include digestive upset, skin irritation, and a garlic-like taste, breath, and body odor.
  • Availability: MSM is easy to purchase and legal. In many countries, DMSO is considered a drug and is available only by prescription or as an industrial solvent.

While both DMSO and MSM have shown potential in treating arthritis and other conditions, more research is needed to determine their effectiveness and safety. It is essential to consult your healthcare provider before using either DMSO or MSM for any health condition.

Comparative Table: DMSO vs MSM

DMSO (dimethyl sulfoxide) and MSM (methylsulfonylmethane) are both organosulfur compounds, but they differ in their physical properties and use. Here is a table comparing the two:

Property DMSO MSM
Chemical Formula (CH3)2SO (CH3)2SO2
Phase at Room Temperature Liquid Solid
Geometry Trigonal Pyramidal Trigonal Planar
Usage Topical application, sometimes administered orally or intravenously Sold as a dietary supplement, often in combination with other ingredients
Solubility Soluble in water and other organic solvents Water-soluble powder
Occurrence in Nature Not found naturally Found naturally in fresh fruits, vegetables, milk, fish, and grains

DMSO is a liquid organosulfur compound that is used topically for various applications, including treating arthritis. MSM, on the other hand, is a solid organosulfur compound that is sold as a dietary supplement and is believed to have many of the health benefits of DMSO without the associated risks. However, the safety and effectiveness of both compounds remain uncertain due to the limited research conducted on them.