What is the Difference Between Dermoid and Epidermoid Cyst?

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Dermoid and epidermoid cysts are both benign ectoderm-lined inclusion cysts that contain skin material, but they differ in complexity and contents. Here are the main differences between the two:

  • Dermoid Cysts: These cysts contain hair, sebaceous and sweat glands, and squamous epithelium. They may also contain other materials such as tooth material, oil, or blood. Dermoid cysts typically have a more complex composition due to the presence of these additional components.
  • Epidermoid Cysts: These cysts contain only squamous epithelium and shed skin cells, such as keratin. They are lined with simple skin cells and do not contain hair follicles, hair, or sweat glands. Epidermoid cysts are generally simpler in composition compared to dermoid cysts.

Both dermoid and epidermoid cysts are slow-growing and usually occur in the scalp, skull, or other regions of the head and neck. They may cause symptoms such as pain, tenderness, or cosmetic concerns, depending on their size and location. Treatment for both types of cysts typically involves surgical removal.

Comparative Table: Dermoid vs Epidermoid Cyst

Here is a table summarizing the difference between dermoid and epidermoid cysts:

Feature Dermoid Cyst Epidermoid Cyst
Composition Composed of elements of all layers of skin, including squamous epithelium, hair, sebaceous glands, and fat. Composed strictly of squamous epithelium.
Contents Contains dermal elements such as hair and hair follicles, as well as apocrine, sebaceous, or sweat glands. Contains epithelial cell debris and keratin.
Radiological Characteristics Rare, making up 0.3% of intracranial tumors. More common, making up 0.5–1.5% of intracranial tumors.
Presentation Usually midline lesions that present early. Usually lateral and present later.
Treatment Surgical removal with complete or subtotal resection of the cyst. Surgical removal with complete or subtotal resection of the cyst.

Dermoid and epidermoid cysts are both intracranial developmental lesions, but they have different compositions and contents. Dermoid cysts contain elements of all layers of the skin, whereas epidermoid cysts are composed strictly of squamous epithelium. Both cysts can be successfully treated with surgical removal.