What is the Difference Between Cirrhosis and Hepatitis?

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Cirrhosis and hepatitis are both liver diseases, but they have distinct differences:

  1. Definition: Cirrhosis is the scarring of the liver, which can occur due to various reasons, including chronic hepatitis. Hepatitis, on the other hand, refers to the inflammation and damage of the liver tissue.
  2. Reversibility: Hepatitis may or may not be reversible (curable). Cirrhosis, however, refers to permanent liver scarring.
  3. Development: While some forms of hepatitis may come on very rapidly, cirrhosis tends to develop more gradually. For example, cirrhosis due to hepatitis C usually takes decades to develop.
  4. Causes: Hepatitis can be caused by various factors, including virus infections (hepatitis A, B, and C), food and water contamination (hepatitis A and E), and direct contact with infected bodily fluids (hepatitis B). Cirrhosis, on the other hand, is the final consequence of various liver diseases, including chronic hepatitis.
  5. Symptoms: In the early stages, cirrhosis may not show any symptoms. However, when symptoms do occur, they may include fatigue, weakness, weight loss, nausea, bruising, or bleeding easily, and swelling in the legs, feet, or ankles. Hepatitis, on the other hand, may present symptoms such as jaundice, fever, fatigue, and gastrointestinal issues, depending on the type and severity of the infection.

In summary, hepatitis refers to the inflammation of the liver tissue and may be reversible, while cirrhosis is the permanent scarring of the liver and tends to develop more gradually. Cirrhosis can be caused by various liver diseases, including chronic hepatitis.

Comparative Table: Cirrhosis vs Hepatitis

Here is a table outlining the differences between cirrhosis and hepatitis:

Feature Cirrhosis Hepatitis
Definition Cirrhosis is a condition characterized by permanent scarring of the liver, often as a result of chronic liver disease. Hepatitis, on the other hand, is inflammation of the liver tissue due to various causes, such as viral infections or exposure to toxins.
Reversibility Cirrhosis is considered irreversible, while hepatitis can be reversible or curable depending on the cause.
Causes Cirrhosis can be caused by chronic hepatitis, alcohol abuse, fatty liver disease, and other conditions. Hepatitis can be caused by viral infections (hepatitis A, B, C, D, and E), autoimmune disorders, and exposure to toxins.
Symptoms Symptoms of cirrhosis may include fatigue, bruising or bleeding easily, inability to eat, nausea, ankle/foot/leg swelling, weight loss, itchy skin, and skin/eye discoloration (jaundice). Symptoms of hepatitis can vary depending on the cause but may include nausea, fatigue, abdominal pain, jaundice, and dark urine.
Complications Complications of cirrhosis can include ascites, esophageal and gastric varices, hypersplenism, spontaneous bacterial peritonitis, acute-on-chronic liver failure, and hepatocellular carcinoma (HCC). Complications of hepatitis depend on the cause and severity of the infection.
Treatment Treatment for cirrhosis focuses on managing complications and preventing further liver damage, with an emphasis on lifestyle changes and medication. Treatment for hepatitis depends on the cause and can include antiviral medications, immunosuppressants, or lifestyle changes.