Author
Home > Science > What is the Difference Between Cell Determination and Cell Differentiation?

Guilherme Mazui

•3 minutes to read

What is the Difference Between Cell Determination and Cell Differentiation?

🆚 Go to Comparative Table 🆚

The difference between cell determination and cell differentiation lies in their respective roles in the development and specialization of cells.

  • Cell determination refers to the process of selecting portions of the genome for gene expression in different embryonic cells. It is the process during which a cell commits to becoming a specific cell type, assigning its fate. Determination occurs in totipotent, embryonic stem cells.
  • Cell differentiation refers to the process of specialization of a cell to make it perform a specific function. It follows cell determination and involves the cell elaborating a cell-specific developmental program. Differentiation results in the presence of cell types with clear-cut identities, such as muscle cells, nerve cells, and skin cells.

In summary:

  • Cell determination is the process of assigning a cell's fate, deciding what it will become in the course of normal development.
  • Cell differentiation is the process of functional specialization, transforming the cell into a specific cell type with specialized structure and function.
On this page
  • What is the Difference Between Cell Determination and Cell Differentiation?
  • Comparative Table: Cell Determination vs Cell Differentiation

    • Comparative Table: Cell Determination vs Cell Differentiation

    Here is a table comparing cell determination and cell differentiation:

    Feature Cell Determination Cell Differentiation
    Definition The process of determining the cell's fate, where the cell's genetic expression is determined to perform a specific function. The process of specialization of a cell to make it perform a specific function, resulting in morphological changes.
    Occurrence Occurs during embryogenesis and in totipotent, embryonic stem cells. Follows cell determination and occurs due to the differential expression of genes.
    Asymmetric Segregation of Cytoplasmic Determinants Results in cell determination. Not directly involved in cell differentiation.
    Role Assigns the fate of the cells. Responsible for the functional specialization of the cells.
    Morphological Changes No visible morphological changes during this stage. Results in highly specialized and specific cells.

    In summary, cell determination is the commitment of a cell to a particular fate, while cell differentiation is the process by which a cell actually undergoes those changes that allow it to be specialized and perform its assigned function.

    Read more:

    Guilherme Mazui

    Guilherme Mazui is graduated in journalism from the Federal University of Minas Gerais (UFMG) and a master's degree in Communication from the University of São Paulo (USP). In addition, he has experience in advertising writing and has worked as a content editor in several companies.