What is the Difference Between Calcium Oxalate Monohydrate and Calcium Oxalate Dihydrate?

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Calcium oxalate monohydrate and calcium oxalate dihydrate are both salts of calcium and oxalate anion, but they differ in the number of water molecules attached to their crystal structures. The main differences between them are:

  1. Number of water molecules: Calcium oxalate monohydrate has one water molecule, while calcium oxalate dihydrate has two water molecules attached to its crystal structure.
  2. Crystal shape: Calcium oxalate monohydrate crystals can be dumbbell-shaped, needle-shaped, or oval, with the oval-shaped crystals resembling red blood cells. Calcium oxalate dihydrate crystals are pyramid-shaped and have a jagged, envelope-like appearance.
  3. Hardness: Calcium oxalate monohydrate crystals are harder than calcium oxalate dihydrate crystals, which makes it more difficult to break them up using lithotripsy.
  4. Concentration in urine: Calcium oxalate monohydrate is more often found when elevated levels of urine oxalate are present.

Both types of crystals can contribute to the formation of kidney stones, which can cause pain and discomfort. Factors that increase the risk of developing calcium oxalate kidney stones include a low volume of urine, high levels of calcium in the urine, high levels of oxalate in the urine, low levels of citrate in the urine, and certain medical conditions.

Comparative Table: Calcium Oxalate Monohydrate vs Calcium Oxalate Dihydrate

Calcium oxalate monohydrate and calcium oxalate dihydrate are two different forms of calcium salt that can be found in kidney stones. Here is a table summarizing their differences:

Feature Calcium Oxalate Monohydrate Calcium Oxalate Dihydrate
Hydrate Form Monohydrate (1 water molecule) Dihydrate (2 water molecules)
Crystal Form Harder and more resistant to fragmentation Softer and less resistant to fragmentation
Occurrence in Kidney Stones More common when elevated levels of urine oxalate are present
Molar Mass 146.11 g/mol

Both calcium oxalate monohydrate and calcium oxalate dihydrate are colorless or white when they are anhydrous or hydrated. However, calcium oxalate monohydrate crystals are harder than calcium oxalate dihydrate crystals, making it more difficult to break them up using lithotripsy.