What is the Difference Between Bioreactor and Fermentor?

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The main difference between a bioreactor and a fermentor lies in the types of biochemical reactions they facilitate and the products they produce. Here are the key differences between the two:

  • Bioreactor: A bioreactor is a vessel that facilitates various types of biochemical reactions, including aerobic and anaerobic conditions. Bioreactors are used in the production of pharmaceutical products, vaccines, antibodies, and other biological compounds. They can use mammalian or insect cell populations and can be designed as packed bed, fluidized bed, IVFR, or Airlift bioreactors.
  • Fermentor: A fermentor is a specific type of bioreactor designed for fermentation reactions that occur under anaerobic conditions. Fermentors are used in the production of ethanol, lactic acid, and other products derived from fermentation processes. They typically use fungal or bacterial microorganisms and can be batch, fed-batch, or continuous in design.

In summary, both bioreactors and fermentors are closed systems that carry out biochemical reactions, but bioreactors can handle various types of reactions, while fermentors are specifically designed for fermentation reactions.

Comparative Table: Bioreactor vs Fermentor

Bioreactors and fermentors are both closed systems used for biochemical reactions, but they have some differences in terms of the type of reactions they facilitate and the organisms they work with. Here is a table summarizing the differences between bioreactors and fermentors:

Feature Bioreactor Fermentor
Type of Reaction Can facilitate various types of biochemical reactions Primarily used for fermentation reactions under anaerobic conditions
Organisms Can work with mammalian or insect cell populations Typically used with fungal or bacterial cell populations
Substrates Can use various types of substrates Limited to glucose/glucose-containing substrates
Aeration Can be either aerobic or anaerobic Only anaerobic
Size Range Typically ranges from liters to meters in size Limited to around 2 liters in size
Applications Used in production of pharmaceuticals, vaccines, antibodies, proteins, etc. Mainly used in production of ethanol, lactic acid, etc.

Key points:

  • Bioreactors can facilitate various types of biochemical reactions, while fermentors are specifically designed for fermentation reactions under anaerobic conditions.
  • Bioreactors can work with mammalian or insect cell populations, whereas fermentors typically work with fungal or bacterial cell populations.
  • Bioreactors can use various types of substrates, while fermentors are limited to glucose or glucose-containing substrates.