What is the Difference Between Base Sequence and Amino Acid Sequence?

The main difference between base sequence and amino acid sequence lies in their composition and function.

• Base sequence: Refers to the sequence of nucleotide bases in a DNA or RNA molecule. It is responsible for the formation of either DNA or RNA, which are essential components of the genetic code.
• Amino acid sequence: Refers to the arrangement of amino acids in a protein. It is responsible for the formation of the primary structure of a functional protein, which is important for various biological functions.

Furthermore, there are four different types of nucleotides in a base sequence, while there are twenty different amino acids in an amino acid sequence. In the protein-coding region of a gene, the DNA sequence is interpreted in groups of three nucleotide bases called codons, which specify a single amino acid in a protein.

In summary, base sequences and amino acid sequences are two related sequences that serve different functions in the genetic code:

• Base sequences are the strings of monomers of DNA or RNA, containing the genetic code of the amino acid sequence.
• Amino acid sequences are the strings of amino acids of a protein, formed through the translation of the genetic code in base sequences.

Comparative Table: Base Sequence vs Amino Acid Sequence

The difference between base sequence and amino acid sequence can be summarized as follows:

In summary, the base sequence is the sequence of nucleotide bases in a DNA or RNA molecule, while the amino acid sequence is the arrangement of amino acids in a protein. The base sequence determines the amino acid sequence, which ultimately gives a specific protein.