What is the Difference Between Aspirin and Ibuprofen?

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Aspirin and ibuprofen are both nonsteroidal anti-inflammatory drugs (NSAIDs) used to treat pain, inflammation, and fever, but they have some differences in their properties and effects. Key differences between aspirin and ibuprofen include:

  1. Uses: Aspirin can help reduce fevers and prevent blood clots, while ibuprofen is mostly used for pain relief.
  2. Gastrointestinal side effects: Aspirin is more likely than low-dose ibuprofen to cause gastrointestinal side effects, such as ulcers and bleeding.
  3. Suitable for ongoing conditions: Ibuprofen is preferred over aspirin for ongoing conditions like arthritis, menstrual cramps, and back pain due to its lower risk of gastrointestinal side effects.
  4. Cautions: People with gastrointestinal disorders, bleeding disorders, or hemophilia should avoid aspirin and only take ibuprofen if advised by a doctor.
  5. Combining with other medications: Aspirin and ibuprofen should not be taken together, especially if you are prescribed aspirin to reduce the risk of heart attack or stroke. Consult your doctor before taking any NSAIDs with aspirin, as they may negate the protective effects of aspirin.

Both aspirin and ibuprofen should not be used by young children due to potential complications. For most people, choosing between aspirin and ibuprofen for headaches is a matter of preference, but high doses of aspirin may be particularly effective for treating severe headaches. It is essential to consult a doctor if you're having trouble managing headaches with over-the-counter NSAIDs.

Comparative Table: Aspirin vs Ibuprofen

Here is a table outlining the differences between aspirin and ibuprofen:

Property Aspirin Ibuprofen
Active Ingredient Acetylsalicylic acid Propionic acid
Function Pain relief, fever reduction, blood clot prevention Pain relief, fever reduction, inflammation reduction
Availability Tablet or suppository Tablet, capsule, liquid, or granules
Brand Names Bayer-Aspirin, Alka-Seltzer, Anacin, BC Powder, Bufferin, Ecotrin, Excedrin, Goody’s, Vanquish Advil, Motrin, Nuprin
Side Effects Gastrointestinal side effects more likely, especially at higher doses Gastrointestinal side effects less likely, especially at lower doses
Cautions Not safe for young children due to potential complications Safe for children, but always follow dosage guidelines
Drug Interactions Both aspirin and ibuprofen interact with angiotensin-II receptor blockers (ARBs), diuretics, clopidogrel, warfarin, dabigatran, and aspirin itself Both aspirin and ibuprofen interact with angiotensin-II receptor blockers (ARBs), diuretics, clopidogrel, warfarin, dabigatran, and aspirin itself

Aspirin and ibuprofen are both nonsteroidal anti-inflammatory drugs (NSAIDs) that can help relieve pain, reduce inflammation, and temporarily lower fever. However, there are some differences between the two medications, such as their active ingredients, potential side effects, and cautions for use.