What is the Difference Between Amoebiasis and Giardiasis?

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Amoebiasis and giardiasis are both intestinal diseases caused by parasitic protozoa, but they differ in the causative organisms, affected areas of the gastrointestinal tract, and modes of transmission. Here are the key differences between the two:

  1. Causative organisms: Amoebiasis is caused by Entamoeba histolytica, while giardiasis is caused by Giardia lamblia (also known as G. duodenalis and G. intestinalis).
  2. Affected areas: Amoebiasis is a lower gastrointestinal tract infection, affecting the colon wall. Giardiasis, on the other hand, is an upper gastrointestinal tract infection, affecting the duodenum, jejunum, and ileum.
  3. Transmission: Both amoebiasis and giardiasis are transmitted through the oral-fecal route, via the ingestion of cysts or oocysts. However, amoebiasis can also be transmitted sexually.
  4. Symptoms: Amoebiasis can cause diarrhea, constipation, belly cramps, and flatulence. Giardiasis typically manifests as mild nutrient malabsorption and intestinal uneasiness, but can progress to more acute stages with fatty stool, explosive diarrhea, vomiting, and anorexia.

Both diseases are more prevalent in developing and low-income countries, and proper diagnosis and treatment are essential to prevent morbidity and mortality.

Comparative Table: Amoebiasis vs Giardiasis

Here is a table comparing the differences between Amoebiasis and Giardiasis:

Feature Amoebiasis Giardiasis
Causative Organism Entamoeba histolytica Giardia lamblia (also known as G. duodenalis)
Disease Type Lower gastrointestinal tract infection Upper gastrointestinal tract infection
Organ System Colon wall, may disseminate to other organs Duodenum, jejunum, and ileum
Transmission Ingestion of cysts or oocysts via oral-fecal route Ingestion of cysts via oral-fecal route
Prevalence Estimated 480 million people globally infected Estimated 280 million people worldwide infected
Symptoms Diarrhea, constipation, belly cramps, flatulence Mild nutrient malabsorption, intestinal discomfort, to acute stages with fatty stool, explosive diarrhea, vomiting, and anorexia

Both Amoebiasis and Giardiasis are gastrointestinal tract diseases caused by parasitic protozoa. They occur through the ingestion of infective stages of pathogens, such as cysts or oocysts, and transmit through the oral-fecal route. However, Amoebiasis is a lower gastrointestinal tract infection caused by Entamoeba histolytica, while Giardiasis is an upper gastrointestinal tract infection caused by Giardia lamblia.