What is the Difference Between Allele and Locus?

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The difference between an allele and a locus lies in their definitions and functions in genetics:

  • Allele: An allele is one of the possible forms of a gene. Usually, there are two types of alleles: dominant and recessive. Alleles are responsible for coding a specific trait and are passed down from parents to offspring.
  • Locus: A locus (or loci, plural) is the actual location of the gene on a region of a chromosome. It serves as a genetic marker and is important in gene mapping and constructing a genetic map of an organism.

In summary, an allele is a variant form of a gene that codes for a specific trait, while a locus is the specific location on a chromosome where a gene is found.

Comparative Table: Allele vs Locus

Here is a table comparing the differences between alleles and loci:

Feature Allele Locus
Definition An allele is a variant form of a gene, which varies according to the nucleotide base present at a particular genome location. A locus is the location on the chromosome where a gene is found.
Role Alleles contribute to the diversity in phenotype expression. The locus is the specific chromosomal location where a gene is found.
Inheritance Humans inherit two copies of each allele, one from each parent. Each allele is located at the same place on a chromosome, and there can be multiple alleles at a given locus.
Variations Alleles can be dominant or recessive, paternal or maternal. Not applicable
Number per genome Humans have two copies of each allele. Each gene has one specific locus on a chromosome.

To summarize, alleles are different versions of a gene, and loci are the specific locations on chromosomes where genes are found.